Alexander Rouvinski
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Explore the profile of Alexander Rouvinski including associated specialties, affiliations and a list of published articles.
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25
Citations
1535
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Recent Articles
1.
Kirillov S, Isupov M, Paterson N, Wiener R, Abeldenov S, Saper M, et al.
Biochemistry
. 2024 Dec;
64(1):67-82.
PMID: 39655415
During infections, reactive oxygen species cause DNA damage, including nucleotide base modification. After removal of the defective base, excision repair requires an endonuclease IV (Nfo), which hydrolyzes the phosphodiester bond...
2.
Nandi I, Ramachandran R, Shalev D, Schneidman-Duhovny D, Shtuhin-Rahav R, Melamed-Book N, et al.
Gut Microbes
. 2024 Sep;
16(1):2400575.
PMID: 39312647
Enteropathogenic (EPEC) is a Gram-negative bacterial pathogen that causes persistent diarrhea. Upon attachment to the apical plasma membrane of the intestinal epithelium, the pathogen translocates virulence proteins called effectors into...
3.
Potruch A, Elinav H, Cohen M, Rouvinski A, Polacheck I, Korem M
Microbiol Spectr
. 2024 Aug;
12(10):e0028024.
PMID: 39162550
The minimum inhibitory concentration (MIC) of echinocandins against spp. does not represent the actual inhibition threshold of echinocandins. Therefore, the recommended method to evaluate their activity is determining the minimum...
4.
Orlovetskie N, Mani D, Rouvinski A, Jarrous N
Proc Natl Acad Sci U S A
. 2023 Oct;
120(42):e2307185120.
PMID: 37831743
Precursor tRNAs are transcribed with flanking and intervening sequences known to be processed by specific ribonucleases. Here, we show that transcription complexes of RNA polymerase III assembled on tRNA genes...
5.
Rouvinski A, Friedman A, Kirillov S, Hannink Attal J, Kumari S, Fahoum J, et al.
Sci Rep
. 2023 Aug;
13(1):14165.
PMID: 37644113
The humoral response after the fourth dose of a mRNA vaccine against COVID-19 has not been adequately described in elderly recipients, particularly those not exposed previously to SARS-CoV-2. Serum anti-RBD...
6.
Stolovich-Rain M, Kumari S, Friedman A, Kirillov S, Socol Y, Billan M, et al.
Front Immunol
. 2023 Feb;
13:933347.
PMID: 36798518
Intramuscularly administered vaccines stimulate robust serum neutralizing antibodies, yet they are often less competent in eliciting sustainable "sterilizing immunity" at the mucosal level. Our study uncovers a strong temporary neutralizing...
7.
Kumari S, Banerjee S, Kumar M, Hayashi A, Solaimuthu B, Cohen-Kfir E, et al.
Int J Mol Sci
. 2022 Jul;
23(13).
PMID: 35806453
Ufmylation is a posttranslational modification in which the modifier UFM1 is attached to target proteins. This conjugation requires the concerted work of three enzymes named UBA5, UFC1, and UFL1. Initially,...
8.
Vaney M, Dellarole M, Duquerroy S, Medits I, Tsouchnikas G, Rouvinski A, et al.
Nat Commun
. 2022 Jun;
13(1):3718.
PMID: 35764616
The flavivirus envelope glycoproteins prM and E drive the assembly of icosahedral, spiky immature particles that bud across the membrane of the endoplasmic reticulum. Maturation into infectious virions in the...
9.
Sharma A, Zhang X, Dejnirattisai W, Dai X, Gong D, Wongwiwat W, et al.
Cell
. 2021 Dec;
184(25):6052-6066.e18.
PMID: 34852239
The human monoclonal antibody C10 exhibits extraordinary cross-reactivity, potently neutralizing Zika virus (ZIKV) and the four serotypes of dengue virus (DENV1-DENV4). Here we describe a comparative structure-function analysis of C10...
10.
Slavin M, Zamel J, Zohar K, Eliyahu T, Braitbard M, Brielle E, et al.
Proc Natl Acad Sci U S A
. 2021 Aug;
118(34).
PMID: 34373319
Atomic structures of several proteins from the coronavirus family are still partial or unavailable. A possible reason for this gap is the instability of these proteins outside of the cellular...