Alexander Peter Schwoerer
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Explore the profile of Alexander Peter Schwoerer including associated specialties, affiliations and a list of published articles.
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11
Citations
103
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Recent Articles
1.
Schwoerer A, Biermann D, Ehmke H
Front Physiol
. 2024 Jul;
15:1346093.
PMID: 39022307
Introduction: Ventricular unloading during prolonged bed rest, mechanical circulatory support or microgravity has repeatedly been linked to potentially life-threatening arrhythmias. It is unresolved, whether this arrhythmic phenotype is caused by...
2.
Bender R, Bruhn N, Eisenbarth S, Lemke R, Pantke C, Hampe W, et al.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
. 2023 Nov;
66(12):1353-1362.
PMID: 37964045
In October 2019, an integrated dentistry program (iMED DENT) was implemented at the University of Hamburg and was the first of its kind in Germany. This model curriculum builds on...
3.
Heinrich T, Sehner S, Wageringel I, Ehmke H, Schwoerer A
BMC Med Educ
. 2022 Jul;
22(1):515.
PMID: 35778720
Background: E-learning based laboratory classes can replace or enhance in-classroom laboratories. They typically offer temporal flexibility, self-determined learning speed, repeatability and do not require supervision or face-to-face contact. The aim...
4.
Pecha S, Yorgan K, Rohl M, Geertz B, Hansen A, Weinberger F, et al.
Sci Rep
. 2019 Jul;
9(1):9831.
PMID: 31285568
Human iPSC-derived engineered heart tissue (hEHT) has been used to remuscularize injured hearts in a guinea pig infarction model. While beneficial effects on cardiac remodeling have been demonstrated, the arrhythmogenic...
5.
Westhofen S, Jelinek M, Dreher L, Biermann D, Martin J, Vitzhum H, et al.
PLoS One
. 2019 Apr;
14(4):e0214513.
PMID: 30978185
Background: Unloading of failing hearts by left ventricular assist devices induces an extensive cardiac remodeling which may lead to a reversal of the initial phenotype-or to its deterioration. The mechanisms...
6.
Jelinek M, Wallach C, Ehmke H, Schwoerer A
Sci Rep
. 2018 Feb;
8(1):2312.
PMID: 29396505
In cardiovascular research, several mouse strains with differing genetic backgrounds are used to investigate mechanisms leading to and sustaining ventricular arrhythmias. The genetic background has been shown to affect the...
7.
El-Armouche A, Schwoerer A, Neuber C, Emons J, Emmons J, Biermann D, et al.
PLoS One
. 2010 Dec;
5(12):e14263.
PMID: 21151612
Background: Mechanical overload leads to cardiac hypertrophy and mechanical unloading to cardiac atrophy. Both conditions produce similar transcriptional changes including a re-expression of fetal genes, despite obvious differences in phenotype....
8.
Schwoerer A, Melnychenko I, Goltz D, Hedinger N, Broichhausen I, El-Armouche A, et al.
J Mol Cell Cardiol
. 2008 Aug;
45(5):633-41.
PMID: 18721926
Cardiac unloading with left ventricular assist devices is increasingly used to treat patients with severe heart failure. Unloading has been shown to improve systolic and diastolic function, but its impact...
9.
Wagner M, Goltz D, Stucke C, Schwoerer A, Ehmke H, Volk T
Pflugers Arch
. 2007 Mar;
454(4):595-604.
PMID: 17333248
Inhibition of endothelin-A (ET(A)) receptors has been shown to reduce ventricular electrical abnormalities associated with cardiac failure. In this study, we investigate the effect of ET(A)-receptor inhibition on the development...
10.
Goltz D, Schultz J, Stucke C, Wagner M, Bassalay P, Schwoerer A, et al.
Cardiovasc Res
. 2007 Feb;
74(1):85-95.
PMID: 17289007
Objective: A reduction of the Ca(2+)-independent transient outward potassium current (I(to)) in epicardial but not in endocardial myocytes of the left ventricle has been observed in cardiac hypertrophy and is...