Alexander Lenail
Overview
Explore the profile of Alexander Lenail including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
280
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0
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Recent Articles
1.
Replogle J, Saunders R, Pogson A, Hussmann J, Lenail A, Guna A, et al.
Cell
. 2022 Jun;
185(14):2559-2575.e28.
PMID: 35688146
A central goal of genetics is to define the relationships between genotypes and phenotypes. High-content phenotypic screens such as Perturb-seq (CRISPR-based screens with single-cell RNA-sequencing readouts) enable massively parallel functional...
2.
Gold M, Lenail A, Fraenkel E
Pac Symp Biocomput
. 2019 Apr;
24:374-385.
PMID: 30963076
When analyzing biological data, it can be helpful to consider gene sets, or predefined groups of biologically related genes. Methods exist for identifying gene sets that are differential between conditions,...
3.
Archer T, Ehrenberger T, Mundt F, Gold M, Krug K, Mah C, et al.
Cancer Cell
. 2018 Sep;
34(3):396-410.e8.
PMID: 30205044
There is a pressing need to identify therapeutic targets in tumors with low mutation rates such as the malignant pediatric brain tumor medulloblastoma. To address this challenge, we quantitatively profiled...