Alexander Kuhlemann
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Explore the profile of Alexander Kuhlemann including associated specialties, affiliations and a list of published articles.
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5
Citations
92
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Recent Articles
1.
Helmerich D, Beliu G, Taban D, Meub M, Streit M, Kuhlemann A, et al.
Nat Methods
. 2022 Aug;
19(8):986-994.
PMID: 35915194
Advances in super-resolution microscopy have demonstrated single-molecule localization precisions of a few nanometers. However, translation of such high localization precisions into sub-10-nm spatial resolution in biological samples remains challenging. Here...
2.
Kuhlemann A, Beliu G, Janzen D, Petrini E, Taban D, Helmerich D, et al.
Front Synaptic Neurosci
. 2021 Dec;
13:727406.
PMID: 34899260
Fluorescence labeling of difficult to access protein sites, e.g., in confined compartments, requires small fluorescent labels that can be covalently tethered at well-defined positions with high efficiency. Here, we report...
3.
Bessa-Neto D, Beliu G, Kuhlemann A, Pecoraro V, Doose S, Retailleau N, et al.
Nat Commun
. 2021 Nov;
12(1):6715.
PMID: 34795271
Progress in biological imaging is intrinsically linked to advances in labeling methods. The explosion in the development of high-resolution and super-resolution imaging calls for new approaches to label targets with...
4.
Beliu G, Altrichter S, Guixa-Gonzalez R, Hemberger M, Brauer I, Dahse A, et al.
Mol Cell
. 2021 Jan;
81(5):905-921.e5.
PMID: 33497605
Adhesion G protein-coupled receptors (aGPCRs)/family B2 GPCRs execute critical tasks during development and the operation of organs, and their genetic lesions are associated with human disorders, including cancers. Exceptional structural...
5.
Bortlein C, Draeger A, Schoenauer R, Kuhlemann A, Sauer M, Schneider-Schaulies S, et al.
Front Immunol
. 2018 May;
9:815.
PMID: 29720981
By promoting ceramide release at the cytosolic membrane leaflet, the neutral sphingomyelinase 2 (NSM) is capable of organizing receptor and signalosome segregation. Its role in T cell receptor (TCR) signaling...