Alexander Kraev
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Explore the profile of Alexander Kraev including associated specialties, affiliations and a list of published articles.
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16
Citations
199
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Recent Articles
1.
Burkov A, Kraev A, Grishin M, Vesnin R, Fomin S, Iordanskii A
Polymers (Basel)
. 2021 Apr;
13(7).
PMID: 33808356
Because of the effort to preserve petroleum resources and promote the development of eco-friendly materials, bio-based polymers produced from sustainable resources have attracted great attention. Among them, polylactide (PLA) and...
2.
Kraev A
J Card Fail
. 2018 Jan;
24(2):115-125.
PMID: 29325795
Background: A mouse line with heterozygous transgenic expression of phospholamban carrying a substitution of cysteine for arginine 9 (TgPLN) under the control of α-myosin heavy chain (αMHC) promoter features dilated...
3.
Kraev A, Merritt-Genore H
J Thorac Cardiovasc Surg
. 2017 Mar;
153(6):1434-1436.
PMID: 28274561
No abstract available.
4.
Kraev A
Biol Direct
. 2014 Jul;
9:18.
PMID: 25038798
Unlabelled: Creation of lethal and synthetic lethal mutations in an experimental organism is a cornerstone of genetic dissection of gene function, and is related to the concept of an essential...
5.
Kraeva N, Zvaritch E, Frodis W, Sizova O, Kraev A, MacLennan D, et al.
Anesthesiology
. 2013 Mar;
118(2):344-9.
PMID: 23460944
Background: Malignant hyperthermia (MH, MIM# 145600) is a complex pharmacogenetic disorder that is manifested in predisposed individuals as a potentially lethal reaction to volatile anesthetics and depolarizing muscle relaxants. Studies...
6.
Kraeva N, Zvaritch E, Rossi A, Goonasekera S, Zaid H, Frodis W, et al.
Neuromuscul Disord
. 2012 Nov;
23(2):120-32.
PMID: 23183335
Central core disease, one of the most common congenital myopathies in humans, has been linked to mutations in the RYR1 gene encoding the Ca(2+) release channel of the sarcoplasmic reticulum...
7.
Kraeva N, Riazi S, Loke J, Frodis W, Crossan M, Nolan K, et al.
Can J Anaesth
. 2011 Apr;
58(6):504-13.
PMID: 21455645
Purpose: Malignant hyperthermia (MH) is an autosomal dominant pharmacogenetic disorder that is manifested on exposure of susceptible individuals to halogenated anesthetics or succinylcholine. Since MH is associated primarily with mutations...
8.
Zvaritch E, Kraeva N, Bombardier E, McCloy R, Depreux F, Holmyard D, et al.
Proc Natl Acad Sci U S A
. 2009 Dec;
106(51):21813-8.
PMID: 19959667
Ryr1(I4895T/wt) (IT/+) mice express a knockin mutation corresponding to the human I4898T EC-uncoupling mutation in the type 1 ryanodine receptor/Ca(2+) release channel (RyR1), which causes a severe form of central...
9.
Janowski E, Day R, Kraev A, Roder J, Cleemann L, Morad M
Am J Physiol Heart Circ Physiol
. 2009 Apr;
296(6):H1994-2006.
PMID: 19395557
The function, regulation, and molecular structure of the cardiac Na(+)/Ca(2+) exchangers (NCXs) vary significantly among vertebrates. We previously reported that beta-adrenergic suppression of amphibian cardiac NCX1.1 is associated with specific...
10.
Zvaritch E, Depreux F, Kraeva N, Loy R, Goonasekera S, Boncompagni S, et al.
Proc Natl Acad Sci U S A
. 2007 Nov;
104(47):18537-42.
PMID: 18003898
A heterozygous Ile4898 to Thr (I4898T) mutation in the human type 1 ryanodine receptor/Ca(2+) release channel (RyR1) leads to a severe form of central core disease. We created a mouse...