Alexander Kastner
Overview
Explore the profile of Alexander Kastner including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
15
Citations
93
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Dijkstra M, Schueffl H, Adamova B, Baumfried O, Kastner A, Berger W, et al.
Inorg Chem
. 2025 Jan;
64(5):2554-2566.
PMID: 39878587
Platinum(II) complexes prevail as first-line treatment for many cancers but are associated with serious side effects and resistance development. Picoplatin emerged as a promising alternative to circumvent GSH-induced tumor resistance...
2.
Kastner A, Schueffl H, Yassemipour P, Keppler B, Heffeter P, Kowol C
Angew Chem Weinheim Bergstr Ger
. 2024 Mar;
135(46):e202311468.
PMID: 38516539
No abstract available.
3.
Kastner A, Mendrina T, Babu T, Karmakar S, Poetsch I, Berger W, et al.
Inorg Chem Front
. 2024 Jan;
11(2):534-548.
PMID: 38235273
While platinum-based chemotherapeutic agents have established themselves as indispensable components of anticancer therapy, they are accompanied by a variety of side effects and the rapid occurrence of drug resistance. A...
4.
Gabbrielli T, Insero G, De Regis M, Corrias N, Galli I, Mazzotti D, et al.
Opt Express
. 2023 Oct;
31(21):35330-35342.
PMID: 37859267
Mid-infrared frequency combs are nowadays well-appreciated sources for spectroscopy and frequency metrology. Here, a comprehensive approach for characterizing a difference-frequency-generated mid-infrared frequency comb (DFG-comb) both in the time and in...
5.
Kastner A, Schueffl H, Yassemipour P, Keppler B, Heffeter P, Kowol C
Angew Chem Int Ed Engl
. 2023 Sep;
62(46):e202311468.
PMID: 37703130
Platinum(IV) prodrugs are highly interesting alternatives to platinum(II) anticancer therapeutics due to their increased tumor selectivity and reduced side effects. In contrast to the established theory, we recently observed that...
6.
Kastner A, Mendrina T, Bachmann F, Berger W, Keppler B, Heffeter P, et al.
Inorg Chem Front
. 2023 Jul;
10(14):4126-4138.
PMID: 37440920
Platinum(iv) prodrugs are a promising class of anticancer agents designed to overcome the limitations of conventional platinum(ii) therapeutics. In this work, we present oxaliplatin(iv)-based complexes, which upon reduction, release acetylsalicylic...
7.
Fronik P, Gutmann M, Vician P, Stojanovic M, Kastner A, Heffeter P, et al.
Commun Chem
. 2023 Jan;
5(1):46.
PMID: 36697790
Clinical efficacy of oxaliplatin is frequently limited by severe adverse effects and therapy resistance. Acquired insensitivity to oxaliplatin is, at least in part, associated with elevated levels of glutathione (GSH)....
8.
Fronik P, Poetsch I, Kastner A, Mendrina T, Hager S, Hohenwallner K, et al.
J Med Chem
. 2021 Aug;
64(16):12132-12151.
PMID: 34403254
Chemotherapy with platinum complexes is essential for clinical anticancer therapy. However, due to side effects and drug resistance, further drug improvement is urgently needed. Herein, we report on triple-action platinum(IV)...
9.
Lahnsteiner M, Kastner A, Mayr J, Roller A, Keppler B, Kowol C
Chemistry
. 2020 Sep;
26(68):15867-15870.
PMID: 32871016
Maleimides are essential compounds for drug conjugation reactions via thiols to antibodies, peptides and other targeting units. However, one main drawback is the occurrence of thiol exchange reactions with, for...
10.
Kastner A, Koumarianou G, Glodic P, Samartzis P, Ladda N, Ranecky S, et al.
Phys Chem Chem Phys
. 2020 Mar;
22(14):7404-7411.
PMID: 32215414
Photoelectron circular dichroism (PECD) is a highly sensitive enantiospecific spectroscopy for studying chiral molecules in the gas phase using either single-photon ionization or multiphoton ionization. In the short pulse limit...