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Alexander Judkins

Explore the profile of Alexander Judkins including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 475
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Recent Articles
1.
Bareja R, Ismail M, Martin D, Nayate A, Yadav I, Labbad M, et al.
Radiol Artif Intell . 2024 Aug; 6(5):e230115. PMID: 39166971
Purpose To evaluate nnU-Net-based segmentation models for automated delineation of medulloblastoma tumors on multi-institutional MRI scans. Materials and Methods This retrospective study included 78 pediatric patients (52 male, 26 female),...
2.
Iyer S, Ismail M, Tamrazi B, Salloum R, de Blank P, Margol A, et al.
Front Oncol . 2023 Jan; 12:915143. PMID: 36620600
Introduction: Medulloblastoma (MB) is a malignant, heterogenous brain tumor. Advances in molecular profiling have led to identifying four molecular subgroups of MB (WNT, SHH, Group 3, Group 4), each with...
3.
Whitney J, Dollinger L, Tamrazi B, Hawes D, Couce M, Marcheque J, et al.
J Pathol Inform . 2022 Oct; 13:100090. PMID: 36268104
Molecular subtypes of medulloblastoma [Sonic Hedgehog (SHH), Wingless/INT (WNT), Group 3, and Group 4] are defined by common patterns of gene expression. These differential gene expression patterns appear to result...
4.
Zin F, Cotter J, Haberler C, Dottermusch M, Neumann J, Schuller U, et al.
Brain Pathol . 2021 May; 31(5):e12967. PMID: 33938067
Atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor that may not only contain rhabdoid tumor cells but also poorly differentiated small-round-blue cells as well as areas with mesenchymal or...
5.
Hoffman L, Richardson E, Ho B, Margol A, Reddy A, Lafay-Cousin L, et al.
Neuro Oncol . 2020 Mar; 22(7):944-954. PMID: 32129445
Atypical teratoid rhabdoid tumor (ATRT) is a rare, highly malignant central nervous system cancer arising in infants and younger children, historically considered to be homogeneous, monogenic, and incurable. Recent use...
6.
Li W, Buckley J, Sanchez-Lara P, Maglinte D, Viduetsky L, Tatarinova T, et al.
J Mol Diagn . 2016 May; 18(4):480-93. PMID: 27155049
Retinoblastoma is a childhood eye malignancy that can lead to the loss of vision, eye(s), and sometimes life. The tumors are initiated by inactivating mutations in both alleles of the...
7.
Lee J, Carrer A, Shah S, Snyder N, Wei S, Venneti S, et al.
Cell Metab . 2014 Jul; 20(2):306-319. PMID: 24998913
Histone acetylation plays important roles in gene regulation, DNA replication, and the response to DNA damage, and it is frequently deregulated in tumors. We postulated that tumor cell histone acetylation...
8.
Venkatramani R, Ji L, Lasky J, Haley K, Judkins A, Zhou S, et al.
J Neurooncol . 2013 Mar; 113(2):285-91. PMID: 23508296
This study investigates the outcome of children <10 years old with newly-diagnosed ependymoma treated on the prospective multinational "Head Start" III clinical trial. Between April 2004 and July 2009, 19...
9.
Roullet M, Martinez D, Ma L, Fowler M, McPhail E, Judkins A, et al.
Am J Clin Pathol . 2010 Mar; 133(4):584-91. PMID: 20231612
A diagnosis of composite lymphoma is typically prompted by the observation of morphologic discordance. We present a case of a spleen revealing histologic features of follicular lymphoma, without any indication...
10.
Evans S, Jenkins K, Jenkins W, Dilling T, Judy K, Schrlau A, et al.
Radiat Res . 2009 Jan; 170(6):677-90. PMID: 19138031
Tissue hypoxia results from the interaction of cellular respiration, vascular oxygen carrying capacity, and vessel distribution. We studied the relationship between tumor vasculature and regions of low pO(2) using quantitative...