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Alexander Immel

Explore the profile of Alexander Immel including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 287
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Recent Articles
1.
Menzel M, Martis-Thiele M, Goldschmid H, Ott A, Romanovsky E, Siemanowski-Hrach J, et al.
Eur J Cancer . 2024 Sep; 211:114306. PMID: 39293347
Introduction: Whole Exome Sequencing (WES) has emerged as an efficient tool in clinical cancer diagnostics to broaden the scope from panel-based diagnostics to screening of all genes and enabling robust...
2.
Krebs M, Haller F, Sporl S, Gerhard-Hartmann E, Utpatel K, Maurus K, et al.
Eur J Cancer . 2024 Jun; 207:114144. PMID: 38852290
Purpose: Providing patient access to precision oncology (PO) is a major challenge of clinical oncologists. Here, we provide an easily transferable model from strategic management science to assess the outreach...
3.
Susat J, Lubke H, Immel A, Brinker U, Macane A, Meadows J, et al.
Cell Rep . 2021 Jun; 35(13):109278. PMID: 34192537
A 5,000-year-old Yersinia pestis genome (RV 2039) is reconstructed from a hunter-fisher-gatherer (5300-5050 cal BP) buried at Riņņukalns, Latvia. RV 2039 is the first in a series of ancient strains...
4.
Immel A, Key F, Szolek A, Barquera R, Robinson M, Harrison G, et al.
Mol Biol Evol . 2021 May; 38(10):4059-4076. PMID: 34002224
Pathogens and associated outbreaks of infectious disease exert selective pressure on human populations, and any changes in allele frequencies that result may be especially evident for genes involved in immunity....
5.
Haller M, Callan K, Susat J, Flux A, Immel A, Franke A, et al.
iScience . 2021 May; 24(5):102419. PMID: 33997698
Medieval Europe was repeatedly affected by outbreaks of infectious diseases, some of which reached epidemic proportions. A Late Medieval mass burial next to the Heiligen-Geist-Hospital in Lübeck (present-day Germany) contained...
6.
Hayer S, Brandis D, Immel A, Susat J, Torres-Oliva M, Ewers-Saucedo C, et al.
Sci Rep . 2021 Jan; 11(1):2307. PMID: 33504886
The historical phylogeography of Ostrea edulis was successfully depicted in its native range for the first time using ancient DNA methods on dry shells from museum collections. This research reconstructed...
7.
Immel A, Pierini F, Rinne C, Meadows J, Barquera R, Szolek A, et al.
Commun Biol . 2021 Jan; 4(1):113. PMID: 33495542
The Wartberg culture (WBC, 3500-2800 BCE) dates to the Late Neolithic period, a time of important demographic and cultural transformations in western Europe. We performed genome-wide analyses of 42 individuals...
8.
Susat J, Bonczarowska J, Petersone-Gordina E, Immel A, Nebel A, Gerhards G, et al.
Sci Rep . 2020 Sep; 10(1):14628. PMID: 32884081
Ancient genomic studies have identified Yersinia pestis (Y. pestis) as the causative agent of the second plague pandemic (fourteenth-eighteenth century) that started with the Black Death (1,347-1,353). Most of the...
9.
Barquera R, Hernandez-Zaragoza D, Bravo-Acevedo A, Arrieta-Bolanos E, Clayton S, Acuna-Alonzo V, et al.
Hum Immunol . 2020 Jul; 81(9):461-474. PMID: 32651014
We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) allele groups and alleles by PCR-SSP based typing in a total of 15,318 mixed ancestry Mexicans from all...
10.
Barquera R, Lamnidis T, Lankapalli A, Kocher A, Hernandez-Zaragoza D, Nelson E, et al.
Curr Biol . 2020 May; 30(11):2078-2091.e11. PMID: 32359431
The forced relocation of several thousand Africans during Mexico's historic period has so far been documented mostly through archival sources, which provide only sparse detail on their origins and lived...