Alexander Hayn
Overview
Explore the profile of Alexander Hayn including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
138
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Recent Articles
1.
Sauer F, Grosser S, Shahryari M, Hayn A, Guo J, Braun J, et al.
Adv Sci (Weinh)
. 2023 Aug;
10(26):e2303523.
PMID: 37553780
Cancer progression is caused by genetic changes and associated with various alterations in cell properties, which also affect a tumor's mechanical state. While an increased stiffness has been well known...
2.
Hayn A, Fischer T, Mierke C
Front Cell Dev Biol
. 2023 Jun;
11:1148162.
PMID: 37287457
The majority of investigations of cancer cells have been performed in an oversimplified 2D environment. In the last decade there is a trend toward more sophisticated 3D cell culture model...
3.
Wilharm N, Fischer T, Hayn A, Mayr S
Polymers (Basel)
. 2022 Oct;
14(20).
PMID: 36298012
Biopolymer blends are advantageous materials with novel properties that may show performances way beyond their individual constituents. Collagen elastin hybrid gels are a new representative of such materials as they...
4.
Martinez-Garcia F, Fischer T, Hayn A, Mierke C, Burgess J, Harmsen M
Gels
. 2022 Sep;
8(9).
PMID: 36135247
The extracellular matrix (ECM) is a three-dimensional, acellular scaffold of living tissues. Incorporating the ECM into cell culture models is a goal of cell biology studies and requires biocompatible materials...
5.
PINCH1 Promotes Fibroblast Migration in Extracellular Matrices and Influences Their Mechanophenotype
Mierke C, Hayn A, Fischer T
Front Cell Dev Biol
. 2022 Jun;
10:869563.
PMID: 35652097
Cell migration performs a critical function in numerous physiological processes, including tissue homeostasis or wound healing after tissue injury, as well as pathological processes that include malignant progression of cancer....
6.
Aermes C, Hayn A, Fischer T, Mierke C
Sci Rep
. 2021 May;
11(1):10771.
PMID: 34031462
The knowledge of cell mechanics is required to understand cellular processes and functions, such as the movement of cells, and the development of tissue engineering in cancer therapy. Cell mechanical...
7.
Hayn A, Fischer T, Mierke C
Front Cell Dev Biol
. 2020 Nov;
8:593879.
PMID: 33251219
Cell motility under physiological and pathological conditions including malignant progression of cancer and subsequent metastasis are founded on environmental confinements. During the last two decades, three-dimensional cell migration has been...
8.
Aermes C, Hayn A, Fischer T, Mierke C
Sci Rep
. 2020 Aug;
10(1):13453.
PMID: 32778758
The magnetic tweezer technique has become a versatile tool for unfolding or folding of individual molecules, mainly DNA. In addition to single molecule analysis, the magnetic tweezer can be used...
9.
Fischer T, Hayn A, Mierke C
Front Cell Dev Biol
. 2020 Jun;
8:393.
PMID: 32548118
The migration and invasion of cancer cells through 3D confined extracellular matrices is coupled to cell mechanics and the mechanics of the extracellular matrix. Cell mechanics is mainly determined by...
10.
Fischer T, Hayn A, Mierke C
Sci Rep
. 2019 Jun;
9(1):8352.
PMID: 31175320
The tissue microenvironment is a major contributor to cellular functions, such as cell adhesion, migration and invasion. A critical physical parameter for determining the effect of the microenvironment on cellular...