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Alexander Goihl

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Articles 26
Citations 424
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Recent Articles
1.
Goihl A, Reinhold D, Reinhold A, Schraven B, Kortvelyessy P
Int J Mol Sci . 2024 Mar; 25(5). PMID: 38473828
Limbic encephalitis (LE) due to anti-leucine-rich glioma-inactivated 1 (LGI1) antibodies is an autoimmune disease characterized by distinct clinical features unique to LGI1 LE, such as faciobrachial dystonic seizures. However, it...
2.
Reinhold D, Farztdinov V, Yan Y, Meisel C, Sadlowski H, Kuhn J, et al.
J Neuroinflammation . 2023 Feb; 20(1):30. PMID: 36759861
Patients with COVID-19 can have a variety of neurological symptoms, but the active involvement of central nervous system (CNS) in COVID-19 remains unclear. While routine cerebrospinal fluid (CSF) analyses in...
3.
Ludewig S, Salzburger L, Goihl A, Rohne J, Leypoldt F, Bittner D, et al.
Cells . 2023 Jan; 12(2). PMID: 36672216
Autoimmune encephalitis (AE) associated with autoantibodies against leucine-rich glioma-inactivated protein-1 (LGI1) can present with faciobrachial dystonic seizures (FBDS) and/or limbic encephalitis (LE). The reasons for this heterogeneity in phenotypes are...
4.
Roggenbuck D, Goihl A, Sowa M, Lopens S, Rodiger S, Schierack P, et al.
Clin Immunol . 2023 Jan; 247:109214. PMID: 36608744
Glycoprotein 2 (GP2) is an autoantigen in Crohn's (CD) and coeliac disease (CeD). We assessed GP2-isoform (GP2)-expression in intestinal biopsies of paediatric patients with CD, CeD, ulcerative colitis (UC), and...
5.
Kortvelyessy P, Kuhle J, Duzel E, Vielhaber S, Schmidt C, Heinius A, et al.
Ann Clin Transl Neurol . 2020 Oct; 7(11):2213-2220. PMID: 33030817
Objective: Neurofilament light chain (NfL) has been established as a biomarker of axonal damage in many diseases of the central nervous system (CNS). Increased levels of serum NfL (sNfL) can...
6.
Kortvelyessy P, Goihl A, Guttek K, Schraven B, Pruss H, Reinhold D
Cytokine . 2020 Aug; 135:155226. PMID: 32799011
Changes in levels of cytokines or soluble receptors in biological fluids may provide information on immunological pathomechanisms underlying the respective diseases. Here, we studied cytokine patterns of patients with autoimmune...
7.
Schlor A, Holzlohner P, Listek M, Griess C, Butze M, Micheel B, et al.
N Biotechnol . 2018 Apr; 45:60-68. PMID: 29635104
Pancreatic secretory zymogen-granule membrane glycoprotein 2 (GP2) has been identified as a major autoantigenic target in Crohn's disease patients. It was reported recently that a long (GP2a) and a short...
8.
Mirdamadi Y, Bommhardt U, Goihl A, Guttek K, Zouboulis C, Quist S, et al.
Dermatoendocrinol . 2018 Feb; 9(1):e1356518. PMID: 29484090
Hyper-glycemic food increases insulin-like growth factor 1 (IGF-1) and insulin signaling and regulates endocrine responses and thereby may modulate the course of acne. Inflammation and adaptive immune responses have a...
9.
Ranjan S, Goihl A, Kohli S, Gadi I, Pierau M, Shahzad K, et al.
Nat Commun . 2017 Aug; 8(1):311. PMID: 28827518
Graft-vs.-host disease (GvHD) is a major complication of allogenic hematopoietic stem-cell(HSC) transplantation. GvHD is associated with loss of endothelial thrombomodulin, but the relevance of this for the adaptive immune response...
10.
Rober N, Noss L, Goihl A, Reinhold D, Jahn J, de Laffolie J, et al.
Inflamm Bowel Dis . 2017 Jul; 23(9):1624-1636. PMID: 28691939
Background: Anti-Glycoprotein 2 (GP2) antibodies are associated with a more complicated course of Crohn's disease (CD) in adults. Four different GP2 isoforms with different length and antibody-binding sites have been...