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Alexander G Little

Explore the profile of Alexander G Little including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 242
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Recent Articles
1.
Little A, Seebacher F
J Exp Biol . 2025 Jan; 228(1. PMID: 39783040
Phenotypic plasticity can represent a vital adaptive response to environmental stressors, including those associated with climate change. Despite its evolutionary advantages, the expression of plasticity varies significantly within and among...
2.
Anderson H, Little A, Fisher D, McEwen B, Culbert B, Balshine S, et al.
J Exp Biol . 2024 Feb; 227(4). PMID: 38372043
No abstract available.
3.
Little A, Seebacher F
Philos Trans R Soc Lond B Biol Sci . 2024 Feb; 379(1898):20220515. PMID: 38310937
Hormones regulate most physiological functions and life history from embryonic development to reproduction. In addition to their roles in growth and development, hormones also mediate responses to the abiotic, social...
4.
Seebacher F, Little A
Philos Trans R Soc Lond B Biol Sci . 2024 Feb; 379(1898):20220506. PMID: 38310936
Environmental conditions experienced within and across generations can impact individual phenotypes via so-called 'epigenetic' processes. Here we suggest that endocrine signalling acts as a 'sensor' linking environmental inputs to epigenetic...
5.
Sun X, Arnott S, Little A
Ecotoxicol Environ Saf . 2024 Jan; 269:115899. PMID: 38171229
Stressors can interact to affect animal fitness, but we have limited knowledge about how temporal variation in stressors may impact their combined effect. This limits our ability to predict the...
6.
Wang Y, Little A, Aristizabal M, Robertson R
eNeuro . 2023 Nov; 10(11). PMID: 37932046
Migratory locusts enter a reversible hypometabolic coma to survive environmental anoxia, wherein the cessation of CNS activity is driven by spreading depolarization (SD). While glycolysis is recognized as a crucial...
7.
Little A, Seebacher F
Front Physiol . 2021 Dec; 12:805102. PMID: 34925077
This review serves as an introduction to a special issue of Frontiers in Physiology, focused on the importance of physiological performance curves across phylogenetic and functional boundaries. Biologists have used...
8.
Seebacher F, Little A
Front Physiol . 2021 Oct; 12:733305. PMID: 34658917
Many ectothermic animals can respond to changes in their environment by altering the sensitivities of physiological rates, given sufficient time to do so. In other words, thermal acclimation and developmental...
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Little A, Pamenter M, Sitaraman D, Templeman N, Willmore W, Hedrick M, et al.
Comp Biochem Physiol B Biochem Mol Biol . 2021 Mar; 255:110593. PMID: 33779562
This review serves as an introduction to a Special Issue of Comparative Biochemistry and Physiology, focused on using non-human models to study biomedical physiology. The concept of a model differs...