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Alexander E Salmon

Explore the profile of Alexander E Salmon including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 246
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Recent Articles
1.
Gaffney M, Cooper R, Cava J, Follett H, Salmon A, Freling S, et al.
Exp Biol Med (Maywood) . 2021 Jul; 246(20):2192-2201. PMID: 34308656
images of human cone photoreceptors have been shown to vary in their reflectance both spatially and temporally. While it is generally accepted that the unique anatomy and physiology of the...
2.
Salmon A, Chen R, Atry F, Gaffney M, Merriman D, Gil D, et al.
Transl Vis Sci Technol . 2021 Jul; 10(8):5. PMID: 34232271
Purpose: To assess the performance of two spectral-domain optical coherence tomography-angiography systems in a natural model of hypoperfusion: the hibernating thirteen-lined ground squirrel (13-LGS). Methods: Using a high-speed (130 kHz)...
3.
Salmon A, Cooper R, Chen M, Higgins B, Cava J, Chen N, et al.
Biomed Opt Express . 2021 Jul; 12(6):3142-3168. PMID: 34221651
To mitigate the substantial post-processing burden associated with adaptive optics scanning light ophthalmoscopy (AOSLO), we have developed an open-source, automated AOSLO image processing pipeline with both "live" and "full" modes....
4.
Young J, Keppel T, Waas M, Salmon A, Buchberger A, Skumatz C, et al.
Mol Omics . 2020 Feb; 16(2):126-137. PMID: 32031200
Compared to adults, children experience increased postoperative scarring and inflammation following intraocular surgery. While the underlying causes of the exaggerated immune response in children are not understood, proteins play key...
5.
Linderman R, Cava J, Salmon A, Chui T, Marmorstein A, Lujan B, et al.
Ophthalmol Retina . 2020 Jan; 4(5):535-544. PMID: 31956075
Purpose: To assess the frequency and impact of abnormal foveal avascular zone (FAZ) topography (i.e., a fragmented FAZ) on visual acuity and foveal anatomic features. Design: Prospective, cross-sectional study from...
6.
Huckenpahler A, Carroll J, Salmon A, Sajdak B, Mastey R, Allen K, et al.
Transl Vis Sci Technol . 2019 Dec; 8(6):38. PMID: 31867139
Purpose: To evaluate different methods of studying cone photoreceptor structure in wild-type (WT) and transgenic pigs carrying the human rhodopsin P23H mutant gene (TgP23H). Methods: For in vivo imaging, pigs...
7.
Sajdak B, Salmon A, Linderman R, Cava J, Heitkotter H, Carroll J
PLoS One . 2019 Sep; 14(9):e0223110. PMID: 31557245
Background: The 13-lined ground squirrel (13-LGS) possesses a cone-dominant retina that is highly amenable to non-invasive high-resolution retinal imaging. The ability for longitudinal assessment of a cone-dominant photoreceptor mosaic with...
8.
Sajdak B, Salmon A, Cava J, Allen K, Freling S, Ramamirtham R, et al.
Exp Eye Res . 2019 Jun; 185:107683. PMID: 31158381
Tree shrews are small mammals with excellent vision and are closely related to primates. They have been used extensively as a model for studying refractive development, myopia, and central visual...
9.
Sajdak B, Salmon A, Litts K, Wells C, Allen K, Dubra A, et al.
Vision Res . 2019 Mar; 158:90-99. PMID: 30826354
Cone photoreceptors of the 13-lined ground squirrel (13-LGS) undergo reversible structural changes during hibernation, including cone outer segment disc degeneration and inner segment mitochondria depletion. Here, we evaluated cone structure...
10.
Yu F, Sajdak B, Sikora J, Salmon A, Nagree M, Gurka J, et al.
Am J Pathol . 2018 Nov; 189(2):320-338. PMID: 30472209
Farber disease (FD) is a debilitating lysosomal storage disorder characterized by severe inflammation and neurodegeneration. FD is caused by mutations in the ASAH1 gene, resulting in deficient acid ceramidase (ACDase)...