Alexander C Schmidt
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Explore the profile of Alexander C Schmidt including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
861
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Recent Articles
21.
Schaap-Nutt A, Liesman R, Bartlett E, Scull M, Collins P, Pickles R, et al.
Virology
. 2012 Sep;
433(2):320-8.
PMID: 22959894
Human parainfluenza viruses (PIVs) cause acute respiratory illness in children, the elderly, and immunocompromised patients. PIV3 is a common cause of bronchiolitis and pneumonia, whereas PIV1 and 2 are frequent...
22.
Schomacker H, Schaap-Nutt A, Collins P, Schmidt A
Curr Opin Virol
. 2012 Jun;
2(3):294-9.
PMID: 22709516
Human parainfluenza viruses (HPIVs) are a common cause of acute respiratory illness throughout life. Infants, children, and the immunocompromised are the most likely to develop severe disease. HPIV1 and HPIV2...
23.
Schomacker H, Hebner R, Boonyaratanakornkit J, Surman S, Amaro-Carambot E, Collins P, et al.
PLoS One
. 2012 Feb;
7(2):e28382.
PMID: 22355301
Interferons (IFNs) play a crucial role in the antiviral immune response. Whereas the C proteins of wild-type human parainfluenza virus type 1 (WT HPIV1) inhibit both IFN-β induction and signaling,...
24.
Karron R, Thumar B, Schappell E, Surman S, Murphy B, Collins P, et al.
Vaccine
. 2011 Dec;
30(26):3975-81.
PMID: 22178099
Human parainfluenza virus type 3 (HPIV3) is an important cause of lower respiratory tract illness in children, yet a licensed vaccine or antiviral drug is not available. We evaluated the...
25.
Schmidt A, Schaap-Nutt A, Bartlett E, Schomacker H, Boonyaratanakornkit J, Karron R, et al.
Expert Rev Respir Med
. 2011 Aug;
5(4):515-26.
PMID: 21859271
In children under 5 years of age, human parainfluenza viruses (HPIVs) as a group are the second most common etiology of acute respiratory illness leading to hospitalization, surpassed only by...
26.
Schmidt A
Semin Respir Crit Care Med
. 2011 Aug;
32(4):527-40.
PMID: 21858754
Viral respiratory infections cause significant morbidity and mortality in infants and young children as well as in at-risk adults and the elderly. Although many viral pathogens are capable of causing...
27.
Durbin A, Whitehead S, Shaffer D, Elwood D, Wanionek K, Thumar B, et al.
PLoS Negl Trop Dis
. 2011 Aug;
5(8):e1267.
PMID: 21829748
Dengue is an emerging infectious disease that has become the most important arboviral infection worldwide. There are four serotypes of dengue virus, DENV-1, DENV-2, DENV-3, and DENV-4, each capable of...
28.
Karron R, Casey R, Thumar B, Surman S, Murphy B, Collins P, et al.
Pediatr Infect Dis J
. 2011 Aug;
30(10):e186-91.
PMID: 21829138
Background: Human parainfluenza virus type 3 (HPIV3) is an important yet underappreciated cause of lower respiratory tract illness in children, and a licensed vaccine is not yet available. Methods: A...
29.
Durbin A, Kirkpatrick B, Pierce K, Schmidt A, Whitehead S
Vaccine
. 2011 Jul;
29(42):7242-50.
PMID: 21781997
The Laboratory of Infectious Diseases at the National Institute of Allergy and Infectious Diseases, National Institutes of Health has been engaged in an effort to develop a safe, efficacious, and...
30.
Schaap-Nutt A, Higgins C, Amaro-Carambot E, Nolan S, DAngelo C, Murphy B, et al.
J Virol
. 2011 Feb;
85(8):4007-19.
PMID: 21289116
Human parainfluenza virus type 2 (HPIV-2), an important pediatric respiratory pathogen, encodes a V protein that inhibits type I interferon (IFN) induction and signaling. Using reverse genetics, we attempted the...