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Alexander Berndt

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Articles 90
Citations 1378
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Recent Articles
1.
Forndran T, Grosse S, Weber G, Hausdorf L, Samsel D, Berndt A, et al.
Placenta . 2024 Sep; PMID: 39307624
In contrast to other tissues, the placenta consists of numerous functionally different cell types, distributed in a markedly dissimilar manner within one placenta and between different cases. To evaluate pathology-specific...
2.
Singerer I, Tempel L, Gruen K, Heiss J, Gutte C, Matasci M, et al.
Cardiovasc Res . 2024 Jul; 120(12):1485-1497. PMID: 39023231
Aims: Pulmonary vascular and right ventricular (RV) remodelling processes are important for development and progression of pulmonary hypertension (PH). The current study analysed the functional role of the extra domain...
3.
Ma Y, Nenkov M, Berndt A, Abubrig M, Schmidt M, Sandhaus T, et al.
Cancers (Basel) . 2024 Mar; 16(6). PMID: 38539505
Abnormal expression of ACSL members 1, 3, 4, 5, and 6 is frequently seen in human cancer; however, their clinical relevance is unclear. In this study, we analyzed the expression...
4.
Wulf S, Mizko L, Herrmann K, Sanchez-Carbonell M, Urbach A, Lemke C, et al.
Biomolecules . 2023 Jul; 13(7). PMID: 37509073
The mitogen-activated protein kinase organizer 1 (MORG1) is a scaffold molecule for the ERK signaling pathway, but also binds to prolyl-hydroxylase 3 and modulates HIFα expression. To obtain further insight...
5.
Heiss J, Grun K, Tempel L, Matasci M, Schrepper A, Schwarzer M, et al.
Eur J Clin Invest . 2022 Nov; 53(3):e13907. PMID: 36377348
Aims: Pulmonary hypertension (PH) is accompanied by pulmonary vascular remodelling. By targeted delivery of Interleukin-9 (IL9) via the immunocytokine F8IL9, beneficial effects could be demonstrated in a mouse model of...
6.
Berndt A, Gassler N, Franz M
Cancers (Basel) . 2022 Oct; 14(19). PMID: 36230826
Invasion of the connective tissue by carcinoma cells is accompanied by disintegration and reorganization of the hemidesmosomes, which connect the basement membrane to the basal epithelial cells. In terms of...
7.
Ehsani M, Bartsch S, Rasa S, Dittmann J, Pungsrinont T, Neubert L, et al.
Oncogene . 2022 May; 41(23):3263-3277. PMID: 35513564
Castration-resistant prostate cancer (CRPC) is an aggressive lethal form of prostate cancer (PCa). Atraric acid (AA) not only inhibits the wild-type androgen receptor (AR) but also those AR mutants that...
8.
Pinessi D, Resovi A, Sangalli F, Morosi L, Zentilin L, Borsotti P, et al.
Matrix Biol . 2021 Oct; 103-104:22-36. PMID: 34653669
The disorganized and inefficient tumor vasculature is a major obstacle to the delivery and efficacy of antineoplastic treatments. Antiangiogenic agents can normalize the tumor vessels, improving vessel function and boosting...
9.
Baz L, Rossberg M, Grun K, Kretzschmar D, Berndt A, Schulze P, et al.
J Clin Med . 2021 Jul; 10(12). PMID: 34207881
Background And Aims: Pulmonary Hypertension (PH) represents an aetiologically and clinically heterogeneous disorder accompanied by a severely impaired prognosis. Key steps of PH pathogenesis are vascular and right ventricular myocardial...
10.
Resovi A, Borsotti P, Ceruti T, Passoni A, Zucchetti M, Berndt A, et al.
Cells . 2020 Apr; 9(4). PMID: 32294968
The prominent desmoplastic stroma of pancreatic ductal adenocarcinoma (PDAC) is a determinant factor in tumor progression and a major barrier to the access of chemotherapy. The PDAC microenvironment therefore appears...