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Alexander A Terentiev

Explore the profile of Alexander A Terentiev including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 421
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Recent Articles
1.
Mokhosoev I, Astakhov D, Terentiev A, Moldogazieva N
Cells . 2024 Dec; 13(23). PMID: 39682707
Background: Cytochromes P450 (CYPs) are heme-containing oxidoreductase enzymes with mono-oxygenase activity. Human CYPs catalyze the oxidation of a great variety of chemicals, including xenobiotics, steroid hormones, vitamins, bile acids, procarcinogens,...
2.
Mokhosoev I, Astakhov D, Terentiev A, Moldogazieva N
Prog Biophys Mol Biol . 2024 Sep; 193:19-34. PMID: 39245215
Superfamily of cytochromes P450 (CYPs) is composed of heme-thiolate-containing monooxygenase enzymes, which play crucial roles in the biosynthesis, bioactivation, and detoxification of a variety of organic compounds, both endogenic and...
3.
Moldogazieva N, Zavadskiy S, Astakhov D, Terentiev A
Biochem Biophys Res Commun . 2023 Nov; 687:149167. PMID: 37939506
Under the exposure of lipids to reactive oxygen species (ROS), lipid peroxidation proceeds non-enzymatically and generates an extremely heterogeneous mixture of reactive carbonyl species (RCS). Among them, HNE, HHE, MDA,...
4.
Zavadskiy S, Gruzdov D, Sologova S, Terentiev A, Moldogazieva N
Antioxidants (Basel) . 2023 Jan; 12(1). PMID: 36670957
Short linear motifs (SLiMs) are evolutionarily conserved functional modules of proteins composed of 3 to 10 residues and involved in multiple cellular functions. Here, we performed a search for SLiMs...
5.
Moldogazieva N, Zavadskiy S, Sologova S, Mokhosoev I, Terentiev A
Expert Rev Mol Diagn . 2021 Sep; 21(11):1147-1164. PMID: 34582293
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and the third cancer-related cause of death worldwide. In recent years, several systemic therapy drugs including sorafenib, lenvatinib, regorafenib, cabozantinib,...
6.
Moldogazieva N, Zavadskiy S, Terentiev A
Cancer Genomics Proteomics . 2021 May; 18(3 Suppl):369-383. PMID: 33994362
Hepatocellular carcinoma (HCC) is the sixth most frequently diagnosed cancer and the third leading cause of cancer-related deaths worldwide. Advanced-stage HCC patients have poor survival rates and this requires the...
7.
Moldogazieva N, Mokhosoev I, Zavadskiy S, Terentiev A
Biomedicines . 2021 Feb; 9(2). PMID: 33562077
Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver with high morbidity and mortality rates worldwide. Since 1963, when alpha-fetoprotein (AFP) was discovered as a first HCC...
8.
Moldogazieva N, Mokhosoev I, Terentiev A
Cancers (Basel) . 2020 Apr; 12(4). PMID: 32252351
It has been long recognized that cancer cells reprogram their metabolism under hypoxia conditions due to a shift from oxidative phosphorylation (OXPHOS) to glycolysis in order to meet elevated requirements...
9.
Moldogazieva N, Ostroverkhova D, Kuzmich N, Kadochnikov V, Terentiev A, Porozov Y
Int J Mol Sci . 2020 Feb; 21(3). PMID: 32019136
Alpha-fetoprotein (AFP) is a major embryo- and tumor-associated protein capable of binding and transporting a variety of hydrophobic ligands, including estrogens. AFP has been shown to inhibit estrogen receptor (ER)-positive...
10.
Moldogazieva N, Mokhosoev I, Melnikova T, Porozov Y, Terentiev A
Oxid Med Cell Longev . 2019 Sep; 2019:3085756. PMID: 31485289
Oxidative stress is a consequence of the use of oxygen in aerobic respiration by living organisms and is denoted as a persistent condition of an imbalance between the generation of...