Alexander A Makarov
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Explore the profile of Alexander A Makarov including associated specialties, affiliations and a list of published articles.
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177
Citations
2632
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Recent Articles
1.
Jager S, Zeller M, Pashkova A, Schulte D, Damoc E, Reiding K, et al.
Nat Commun
. 2025 Mar;
16(1):2497.
PMID: 40082474
Recently, a conceptually new mass analyzer was introduced by pairing a quadrupole Orbitrap mass spectrometer with an asymmetric track lossless (Astral™) analyzer. This system provides >200 Hz MS/MS scanning speed,...
2.
Kolobova E, Petrushanko I, Mitkevich V, Makarov A, Grigorova I
Biol Methods Protoc
. 2025 Jan;
10(1):bpaf001.
PMID: 39830230
Alzheimer's disease (AD) is a multifactorial systemic disease that is triggered, at least in part, by the accumulation of β-amyloid (Aβ) peptides in the brain, but it also depends on...
3.
Tolstova A, Adzhubei A, Strelkova M, Makarov A, Mitkevich V
Biophys Rev
. 2025 Jan;
16(6):701-722.
PMID: 39830132
Supplementary Information: The online version contains supplementary material available at 10.1007/s12551-024-01253-y.
4.
Strelnikova P, Zakharova N, Kononikhin A, Bugrova A, Indeykina M, Mitkevich V, et al.
Expert Rev Proteomics
. 2025 Jan;
22(1):11-18.
PMID: 39764651
Introduction: Identifying early risks of developing Alzheimer's disease (AD) is a major challenge as the number of patients with AD steadily increases and requires innovative solutions. Current molecular diagnostic modalities,...
5.
Varshavskaya K, Barykin E, Timoshenko R, Kolmogorov V, Erofeev A, Gorelkin P, et al.
Front Mol Neurosci
. 2024 Nov;
17:1501874.
PMID: 39610710
Post-translational modifications of beta-amyloid (Aβ) play an important role in the pathogenesis of Alzheimer's disease (AD). Aβ modifications such as Ser8 phosphorylation (pS8-Aβ) and Asp7 isomerization (iso-Aβ) can significantly alter...
6.
Strelkova M, Tolstova A, Mitkevich V, Petrushanko I, Makarov A
Int J Mol Sci
. 2024 Nov;
25(22).
PMID: 39596456
Src kinase is one of the key regulators of cellular metabolism and is dysregulated in numerous diseases, including cancer, neurodegenerative diseases, and particularly Alzheimer's disease. Despite its therapeutic importance, its...
7.
Vaneev A, Gorelkin P, Barykin E, Kolmogorov V, Timoshenko R, Mitkevich V, et al.
Chembiochem
. 2024 Nov;
26(1):e202400786.
PMID: 39548866
This study aims to investigate the potential role of antioxidants in oxidative stress and its consequent impact on the mechanical properties of neuronal cells, particularly the stress induced by amyloid-beta...
8.
Kononikhin A, Starodubtseva N, Brzhozovskiy A, Tokareva A, Kashirina D, Zakharova N, et al.
Biomedicines
. 2024 Oct;
12(10).
PMID: 39457715
Background/objectives: The development of blood tests for the early detection of individual predisposition to socially significant diseases remains a pressing issue. Methods: In this pilot study, multiple reaction monitoring mass...
9.
Kolobova E, Petrushanko I, Mitkevich V, Makarov A, Grigorova I
Cells
. 2024 Oct;
13(19.
PMID: 39404388
Alzheimer's disease (AD) is associated with the accumulation of β-amyloids (Aβs) and the formation of Aβ plaques in the brain. Various structural forms and isoforms of Aβs that have variable...
10.
Le Huray K, Worner T, Moreira T, Dembek M, Reinhardt-Szyba M, Devine P, et al.
ACS Cent Sci
. 2024 Sep;
10(8):1548-1561.
PMID: 39220705
Great progress has been made in the detection of large biomolecular analytes by native mass spectrometry; however, characterizing highly heterogeneous samples remains challenging due to the presence of many overlapping...