Alex Zijdenbos
Overview
Explore the profile of Alex Zijdenbos including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
2231
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Recent Articles
1.
Forsberg L, Sigurdsson S, Fredriksson J, Egilsdottir A, Oskarsdottir B, Kjartansson O, et al.
Med Image Anal
. 2017 May;
39:133-144.
PMID: 28501699
Quantitative analyses of brain structures from Magnetic Resonance (MR) image data are often performed using automatic segmentation algorithms. Many of these algorithms rely on templates and atlases in a common...
2.
Hibar D, Adams H, Jahanshad N, Chauhan G, Stein J, Hofer E, et al.
Nat Commun
. 2017 Jan;
8:13624.
PMID: 28098162
The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several common...
3.
Adams H, Hibar D, Chouraki V, Stein J, Nyquist P, Renteria M, et al.
Nat Neurosci
. 2016 Nov;
19(12):1569-1582.
PMID: 27694991
Intracranial volume reflects the maximally attained brain size during development, and remains stable with loss of tissue in late life. It is highly heritable, but the underlying genes remain largely...
4.
Hofer E, Cavalieri M, Bis J, DeCarli C, Fornage M, Sigurdsson S, et al.
Stroke
. 2015 Oct;
46(11):3048-57.
PMID: 26451028
Background And Purpose: White matter lesion (WML) progression on magnetic resonance imaging is related to cognitive decline and stroke, but its determinants besides baseline WML burden are largely unknown. Here,...
5.
Verhaaren B, Debette S, Bis J, Smith J, Ikram M, Adams H, et al.
Circ Cardiovasc Genet
. 2015 Feb;
8(2):398-409.
PMID: 25663218
Background: The burden of cerebral white matter hyperintensities (WMH) is associated with an increased risk of stroke, dementia, and death. WMH are highly heritable, but their genetic underpinnings are incompletely...
6.
Bis J, DeCarli C, Smith A, van der Lijn F, Crivello F, Fornage M, et al.
Nat Genet
. 2012 Apr;
44(5):545-51.
PMID: 22504421
Aging is associated with reductions in hippocampal volume that are accelerated by Alzheimer's disease and vascular risk factors. Our genome-wide association study (GWAS) of dementia-free persons (n = 9,232) identified...
7.
Sigurdsson S, Aspelund T, Forsberg L, Fredriksson J, Kjartansson O, Oskarsdottir B, et al.
Neuroimage
. 2011 Nov;
59(4):3862-3870.
PMID: 22119006
Imaging studies have reported conflicting findings on how brain structure differs with age and sex. This may be explained by discrepancies and limitations in study population and study design. We...
8.
Proal E, Reiss P, Klein R, Mannuzza S, Gotimer K, Ramos-Olazagasti M, et al.
Arch Gen Psychiatry
. 2011 Nov;
68(11):1122-34.
PMID: 22065528
Context: Volumetric studies have reported relatively decreased cortical thickness and gray matter volumes in adults with attention-deficit/hyperactivity disorder (ADHD) whose childhood status was retrospectively recalled. We present, to our knowledge,...
9.
Fornage M, Debette S, Bis J, Schmidt H, Ikram M, Dufouil C, et al.
Ann Neurol
. 2011 Jun;
69(6):928-39.
PMID: 21681796
Objective: White matter hyperintensities (WMHs) detectable by magnetic resonance imaging are part of the spectrum of vascular injury associated with aging of the brain and are thought to reflect ischemic...
10.
He Y, Dagher A, Chen Z, Charil A, Zijdenbos A, Worsley K, et al.
Brain
. 2009 May;
132(Pt 12):3366-79.
PMID: 19439423
White matter tracts, which play a crucial role in the coordination of information flow between different regions of grey matter, are particularly vulnerable to multiple sclerosis. Many studies have shown...