» Authors » Alex Valenzuela

Alex Valenzuela

Explore the profile of Alex Valenzuela including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 12
Citations 306
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Wang H, Medina R, Ye J, Zhang Y, Chakraborty S, Valenzuela A, et al.
Adv Sci (Weinh) . 2024 Feb; 11(14):e2308280. PMID: 38298111
Despite strides in immunotherapy, glioblastoma multiforme (GBM) remains challenging due to low inherent immunogenicity and suppressive tumor microenvironment. Converting "cold" GBMs to "hot" is crucial for immune activation and improved...
2.
Ye J, Wang H, Medina R, Chakraborty S, Sun M, Valenzuela A, et al.
J Exp Clin Cancer Res . 2023 Jul; 42(1):163. PMID: 37434263
Background: Autologous tumor cell-based vaccines (ATVs) aim to prevent and treat tumor metastasis by activating patient-specific tumor antigens to induce immune memory. However, their clinical efficacy is limited. Mannan-BAM (MB),...
3.
Wu S, Ma X, Zhou A, Valenzuela A, Zhou K, Li Y
Sci Adv . 2021 Sep; 7(38):eabh4048. PMID: 34533983
Strigolactones (SLs) are a class of phytohormones playing diverse roles in plant growth and development, yet the limited access to SLs is largely impeding SL-based foundational investigations and applications. Here,...
4.
Mateus J, Rivera C, Omeara M, Valenzuela A, Lizcano F
Clin Diabetes Endocrinol . 2020 Sep; 6:16. PMID: 32864159
Background: Diabetes mellitus with autosomal dominant inheritance, such as maturity-onset diabetes of the young (MODY), is a genetic form of diabetes mellitus. MODY is a type of monogenic diabetes mellitus...
5.
Valenzuela A, Meservey L, Nguyen H, Fu M
Trends Cell Biol . 2020 Sep; 30(10):792-804. PMID: 32863092
Classically, animal cells nucleate or form new microtubules off the perinuclear centrosome. In recent years, the Golgi outpost has emerged as a satellite organelle that can function as an acentrosomal...
6.
Garcia G, Valenzuela A, Manzoni T, Vaughan A, Lopez C
Am J Pathol . 2019 Dec; 190(3):543-553. PMID: 31866346
Chronic obstructive pulmonary disease (COPD) and asthma remain prevalent human lung diseases. Variability in epithelial and inflammatory components that results in pathologic heterogeneity complicates the development of treatments for these...
7.
Fu M, McAlear T, Nguyen H, Oses-Prieto J, Valenzuela A, Shi R, et al.
Cell . 2019 Sep; 179(1):132-146.e14. PMID: 31522887
Oligodendrocytes extend elaborate microtubule arbors that contact up to 50 axon segments per cell, then spiral around myelin sheaths, penetrating from outer to inner layers. However, how they establish this...
8.
Sengupta S, Tang S, Devine J, Anderson S, Nayak S, Zhang S, et al.
Nat Commun . 2019 Sep; 10(1):4107. PMID: 31511530
Influenza is a leading cause of respiratory mortality and morbidity. While inflammation is essential for fighting infection, a balance of anti-viral defense and host tolerance is necessary for recovery. Circadian...
9.
Aguilera C, Labbe T, Busquets J, Venegas P, Neira C, Valenzuela A
Rev Med Chil . 2019 Jul; 147(4):470-474. PMID: 31344209
Obesity is a global health problem. Its worldwide prevalence has tripled between 1975 and 2016, reaching a prevalence in Chile of 34.4%, according to the National Health Survey 2016-2017. If...
10.
Muallem G, Wagage S, Sun Y, DeLong J, Valenzuela A, Christian D, et al.
PLoS Pathog . 2017 Jan; 13(1):e1006173. PMID: 28129374
Respiratory paramyxoviruses are important causes of morbidity and mortality, particularly of infants and the elderly. In humans, a T helper (Th)2-biased immune response to these infections is associated with increased...