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Alex Hobson

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Articles 14
Citations 169
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Recent Articles
1.
Staniszewska A, Gaba K, Patterson B, Wilson S, Bell R, Bicknell C, et al.
Emerg Med J . 2023 Dec; 41(3):153-161. PMID: 38050049
Background: Standardisation of referral pathways and the transfer of patients with acute aortic syndromes (AAS) to regional centres are recommended by NHS England in the Acute Aortic Dissection Toolkit. The...
2.
Hlatky M, Wilding S, Stuart B, Nicholas Z, Shambrook J, Eminton Z, et al.
J Cardiovasc Comput Tomogr . 2022 Oct; 17(1):52-59. PMID: 36216700
Background: FFR assesses the functional significance of lesions seen on CTCA, and may be a more efficient approach to chest pain evaluation. The FORECAST randomized trial found no significant difference...
3.
Stables R, Mullen L, Elguindy M, Nicholas Z, Aboul-Enien Y, Kemp I, et al.
Circulation . 2022 Aug; 146(9):687-698. PMID: 35946404
Background: Measurement of fractional flow reserve (FFR) has an established role in guiding percutaneous coronary intervention. We tested the hypothesis that, at the stage of diagnostic invasive coronary angiography, systematic...
4.
Maznyczka A, Rajkumar C, Hobson A, Haworth P
BMJ Case Rep . 2022 Jun; 15(6). PMID: 35688575
We present a case of angina, where extreme coronary tortuosity affected invasive physiology interpretation. Extreme coronary tortuosity may lower fractional flow reserve and instantaneous wave-free ratio. Therefore, invasive physiology can...
5.
Mahadevan K, Sharma D, Walker C, Maznyczka A, Hobson A, Strike P, et al.
BMJ Open . 2022 Feb; 12(2):e046231. PMID: 35210332
Objective: Evidence supports improved outcomes and reduced mortality with rapid reperfusion through primary percutaneous coronary intervention (PPCI) for ST-elevation myocardial infarction (STEMI). UK national audit data (Myocardial Ischaemia National Audit...
6.
Maznyczka A, Hobson A, Curzen N, Haworth P
Heart Lung Circ . 2021 Aug; 31(1):e5-e6. PMID: 34454839
No abstract available.
7.
Curzen N, Nicholas Z, Stuart B, Wilding S, Hill K, Shambrook J, et al.
Eur Heart J . 2021 Jul; 42(37):3844-3852. PMID: 34269376
Aims: Fractional flow reserve (FFRCT) using computed tomography coronary angiography (CTCA) determines both the presence of coronary artery disease and vessel-specific ischaemia. We tested whether an evaluation strategy based on...
8.
Mahadevan K, Cowan E, Kalsi N, Bolam H, Arnett R, Hobson A, et al.
Open Heart . 2020 Dec; 7(2). PMID: 33268470
Objective: To understand human factors (HF) contributing to disturbances during invasive cardiac procedures, including frequency and nature of distractions, and assessment of operator workload. Methods: Single centre prospective observational evaluation...
9.
Khanna V, Hobson A, Mikael R, Sambu N, Englyst N, Curzen N
Thromb Haemost . 2014 Mar; 111(6):1150-9. PMID: 24671606
In contrast to short thrombelastography (s-TEG) which utilises adenosine diphosphate (ADP) alone, the VerifyNow P2Y12 assay (VN-P2Y12) additionally uses prostaglandin E1 (PGE1) as agonist to assess response to P2Y12 inhibitors....
10.
Curzen N, Rana O, Nicholas Z, Golledge P, Zaman A, Oldroyd K, et al.
Circ Cardiovasc Interv . 2014 Mar; 7(2):248-55. PMID: 24642999
Background: The use of coronary angiography (CA) for diagnosis and management of chest pain (CP) has several flaws. The assessment of coronary artery disease using fractional flow reserve (FFR) is...