Alex Helkin
Overview
Explore the profile of Alex Helkin including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
109
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0
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Recent Articles
1.
Maier K, Helkin A, Stein J, Yuan H, Seymour K, Ryabtsev B, et al.
Vasc Endovascular Surg
. 2024 Sep;
59(1):39-46.
PMID: 39235354
Introduction: Vascular smooth muscle cells are important in intimal hyperplasia. Thrombospondin-1 is a matricellular protein involved in the vascular injury response. Statins are cholesterol lowering drugs that have beneficial cardiovascular...
2.
Srinivas S, Villarreal M, Baselice H, Bergus K, Waterman B, Henderson K, et al.
J Surg Res
. 2023 Oct;
294:150-159.
PMID: 37890274
Introduction: Surgical emergencies are time sensitive. Identifying patients who may benefit from preoperative goals of care discussions is critical to ensuring that operative intervention aligns with the patient's values. We...
3.
Chawla M, Baselice H, Negash R, Helkin A, Young A
J Surg Res
. 2023 Oct;
294:58-65.
PMID: 37864960
Introduction: Older adults experience higher rates of complications after an emergency exploratory laparotomy (EEL). To better understand the shift to an aging population in the United States, identifying how age...
4.
Villarreal M, Jalilvand A, Schubauer K, Kellet W, DiDonato C, Roberts L, et al.
Surg Infect (Larchmt)
. 2022 Oct;
23(9):801-808.
PMID: 36301537
Necrotizing soft tissue infections (NSTIs) are life-threatening infections requiring prompt intervention. The Distressed Communities Index (DCI) is a comprehensive ranking of socioeconomic well-being based on zip code. We sought to...
5.
Young A, Kaufman E, Hare A, Subramanian M, Keating J, Byrne J, et al.
J Surg Res
. 2021 Aug;
268:540-545.
PMID: 34464891
Background: Falls are the most common cause of injury-related death for patients older than 45. We hypothesized that a machine learning algorithm developed from state-level registry data could make accurate...
6.
Muqri F, Helkin A, Maier K, Gahtan V
J Cell Biochem
. 2020 Apr;
121(10):4154-4165.
PMID: 32348623
The thrombospondins (TSPs), multifunctional matricellular proteins, are known mediators of endothelial cell (EC) angiogenesis and apoptosis. TSP-1, an antiangiogenic molecule, is important in the progression of vascular disease, in part...
7.
Helkin A, Bruch D, Wilson D, Gruessner A, Bader R, Maier K, et al.
Vasc Endovascular Surg
. 2019 Apr;
53(5):379-386.
PMID: 30982448
Introduction: Oral statins reduce intimal hyperplasia (IH) after arterial injury by only ∼25%. Alternative drug delivery systems have gained attention as carriers for hydrophobic drugs. We studied the effects of...
8.
Yepuri N, Costanza M, Helkin A, Cooney R
Trauma Surg Acute Care Open
. 2018 May;
2(1):e000116.
PMID: 29766109
No abstract available.
9.
Helkin A, Jain S, Gruessner A, Fleming M, Kohman L, Costanza M, et al.
Perioper Med (Lond)
. 2017 Dec;
6:23.
PMID: 29238570
Background: The ASA physical classification score has a major impact on the observed/expected (O/E) mortality ratio in the NSQIP General Vascular Mortality Model. The difference in predicted mortality is greatest...
10.
Desai P, Helkin A, Odugbesi A, Stein J, Bruch D, Lawler J, et al.
J Surg Res
. 2017 May;
210:1-7.
PMID: 28457315
Background: Thrombospondin-1 (TSP-1) is functionally important to intimal hyperplasia (IH) development. Statin drugs have beneficial pleiotropic effects, including reduced IH; however, the effect of statins on IH in a TSP-1-independent...