Alex H Mirnezami
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Explore the profile of Alex H Mirnezami including associated specialties, affiliations and a list of published articles.
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19
Citations
648
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Recent Articles
1.
Tiwari A, Lee S, MacCabe T, Woyton M, West C, Micklethwaite R, et al.
Eur J Surg Oncol
. 2025 Mar;
51(5):109724.
PMID: 40022886
Background: Intra-operative electron radiotherapy (IOERT) directly delivers a large fraction of radiation to at-risk margins during surgery. However, the precise benefit of IOERT in patients with locally advanced and locally...
2.
West C, Tiwari A, Salem Y, Woyton M, Alford N, Roy S, et al.
Cancers (Basel)
. 2025 Jan;
17(1.
PMID: 39796738
Conventional pelvic exenteration (PE) comprises the removal of all or most central pelvic organs and is established in clinical practise. Previously, tumours involving bone or lateral sidewall structures were deemed...
3.
West C, Denys A, Rose S, Pape E, van Ramshorst G, Sutton P, et al.
Psychooncology
. 2024 Sep;
33(10):e9316.
PMID: 39349397
Objective: The empty pelvis syndrome (EPS) is common after pelvic exenteration (PE), causing fluid collections, bowel obstruction, perineal sinuses, and fistulas. The best approach to fill the pelvis to mitigate...
4.
Patel B, Bhome R, Liu D, Giovannetti E, Merali N, Primrose J, et al.
Expert Rev Mol Diagn
. 2023 Aug;
23(10):843-849.
PMID: 37599564
Colorectal cancer (CRC) is the 2nd leading cause of cancer-related deaths worldwide, primarily due to the development of metastatic disease. The liver is the most frequently affected site. The metastatic...
5.
McCarthy R, Copson E, Tapper W, Bolton H, Mirnezami A, ONeill J, et al.
Br J Cancer
. 2023 May;
129(3):383-392.
PMID: 37258796
Identifying healthy carriers of germline pathogenic variants in high penetrance cancer susceptibility genes offers the potential for risk-reducing surgery. The NHS England National Genomic Test Directory offers germline and somatic...
6.
Bhome R, Emaduddin M, James V, House L, Thirdborough S, Mellone M, et al.
J Extracell Vesicles
. 2022 May;
11(5):e12226.
PMID: 35595718
Colorectal cancer (CRC) with a mesenchymal gene expression signature has the greatest propensity for distant metastasis and is characterised by the accumulation of cancer-associated fibroblasts in the stroma. We investigated...
7.
Zhang L, Pickard K, Jenei V, Bullock M, Bruce A, Mitter R, et al.
Cancer Res
. 2022 Apr;
82(8):1669.
PMID: 35425964
No abstract available.
8.
Pilkington S, Bhome R, Gilbert S, Harris S, Richardson C, Dudding T, et al.
Colorectal Dis
. 2021 May;
23(9):2436-2446.
PMID: 34032359
Aim: The aim of this study was to investigate changes in bowel function and anorectal physiology (ARP) after anterior resection for colorectal cancer. Method: Patients were recruited from November 2006...
9.
Al-Shamaa Z, Kurnaz S, Duru A, Peppa N, Mirnezami A, Hamady Z
Appl Bionics Biomech
. 2020 Nov;
2020:8824625.
PMID: 33204304
Imbalanced class distribution in the medical dataset is a challenging task that hinders classifying disease correctly. It emerges when the number of healthy class instances being much larger than the...
10.
Banerjee A, Birts C, Darley M, Parker R, Mirnezami A, West J, et al.
Carcinogenesis
. 2019 Jan;
40(7):871-882.
PMID: 30668646
Altered flux through major metabolic pathways is a hallmark of cancer cells and provides opportunities for therapy. Stem cell-like cancer (SCLC) cells can cause metastasis and therapy resistance. They possess...