Alex Cornwell
Overview
Explore the profile of Alex Cornwell including associated specialties, affiliations and a list of published articles.
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5
Citations
12
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Recent Articles
1.
Johnson B, Farkas D, El-Mergawy R, Adair J, Elhance A, Eltobgy M, et al.
Nat Commun
. 2024 Jul;
15(1):6172.
PMID: 39039092
The severity of bacterial pneumonia can be worsened by impaired innate immunity resulting in ineffective pathogen clearance. We describe a mitochondrial protein, aspartyl-tRNA synthetase (DARS2), which is released in circulation...
2.
Cornwell A, Badiei A
Exp Eye Res
. 2023 Jul;
234:109568.
PMID: 37460081
The discovery of the hydrogen sulfide (HS) and the transsulfuration pathway (TSP) responsible for its synthesis in the mammalian retina has highlighted this molecule's wide range of physiological processes that...
3.
Cornwell A, Ziolkowski H, Badiei A
Biomolecules
. 2023 May;
13(5).
PMID: 37238640
This study investigated the critical role of Glut1-mediated glucose metabolism in the inflammatory response of macrophages, which are energy-intensive cells within the innate immune system. Inflammation leads to increased Glut1...
4.
From Gasotransmitter to Immunomodulator: The Emerging Role of Hydrogen Sulfide in Macrophage Biology
Cornwell A, Badiei A
Antioxidants (Basel)
. 2023 Apr;
12(4).
PMID: 37107310
Hydrogen sulfide (HS) has been increasingly recognized as a crucial inflammatory mediator in immune cells, particularly macrophages, due to its direct and indirect effects on cellular signaling, redox homeostasis, and...
5.
Cornwell A, Fedotova S, Cowan S, Badiei A
PLoS One
. 2022 Dec;
17(12):e0278910.
PMID: 36520801
Macrophages play a crucial role in inflammation, a defense mechanism of the innate immune system. Metabolic function powered by glucose transporter isoform 1 (Glut1) is necessary for macrophage activity during...