Alex Buchberger
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Explore the profile of Alex Buchberger including associated specialties, affiliations and a list of published articles.
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10
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66
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Recent Articles
1.
Reyes L, Naser L, Weiner W, Thifault D, Stahl E, McCreary L, et al.
Nat Commun
. 2025 Feb;
16(1):2060.
PMID: 40021642
The focal adhesion kinase (FAK) scaffold provides FAK-targeted cancer therapeutics with greater efficacy and specificity than traditional kinase inhibitors. The FAK scaffold function largely involves the interaction between FAK's focal...
2.
Simmons C, Buchberger A, Henry S, Novacek A, Fahmi N, MacCulloch T, et al.
J Am Chem Soc
. 2023 Nov;
145(48):26075-26085.
PMID: 37987645
The structural analysis of guest molecules in rationally designed and self-assembling DNA crystals has proven an elusive goal since its conception. Oligonucleotide frameworks provide an especially attractive route toward studying...
3.
Simmons C, Buchberger A, Henry S, Novacek A, Fahmi N, MacCulloch T, et al.
bioRxiv
. 2023 Oct;
PMID: 37873139
The structural analysis of guest molecules in rationally designed and self-assembling DNA crystals has proven elusive since its conception. Oligonucleotide frameworks provide an especially attractive route towards studying DNA-binding molecules...
4.
Narayanan R, Prasad A, Buchberger A, Zou L, Bernal-Chanchavac J, MacCulloch T, et al.
Small
. 2023 Oct;
20(9):e2307585.
PMID: 37849034
The combination of multiple orthogonal interactions enables hierarchical complexity in self-assembled nanoscale materials. Here, efficient supramolecular polymerization of DNA origami nanostructures is demonstrated using a multivalent display of small molecule...
5.
Buchberger A, Al-Amin M, Simmons C, Stephanopoulos N
Chembiochem
. 2023 Apr;
24(17):e202300223.
PMID: 37099451
Peptides and DNA are two of the most commonly used self-assembling biological molecules for the construction of nanomaterials. However, there are only a few examples that combine these two self-assembly...
6.
Buchberger A, Riker K, Bernal-Chanchavac J, Narayanan R, Simmons C, Fahmi N, et al.
ACS Appl Bio Mater
. 2022 Sep;
PMID: 36108278
The integration of proteins with DNA nanotechnology would enable materials with diverse applications in biology, medicine, and engineering. Here, we describe a method for the incorporation of bioactive fibronectin domain...
7.
Simmons C, MacCulloch T, Krepl M, Matthies M, Buchberger A, Crawford I, et al.
Nat Commun
. 2022 Jun;
13(1):3112.
PMID: 35662248
The programmable synthesis of rationally engineered crystal architectures for the precise arrangement of molecular species is a foundational goal in nanotechnology, and DNA has become one of the most prominent...
8.
Buchberger A, Saini H, Eliato K, Zare A, Merkley R, Xu Y, et al.
Chembiochem
. 2021 Jan;
22(10):1755-1760.
PMID: 33484601
Biomaterials with dynamically tunable properties are critical for a range of applications in regenerative medicine and basic biology. In this work, we show the reversible control of gelatin methacrylate (GelMA)...
9.
Buchberger A, Simmons C, Fahmi N, Freeman R, Stephanopoulos N
J Am Chem Soc
. 2019 Dec;
142(3):1406-1416.
PMID: 31820959
DNA and peptides are two of the most commonly used biomolecules for building self-assembling materials, but few examples exist of hybrid nanostructures that contain both components. Here we report the...
10.
Mahatmanto T, Azizah I, Buchberger A, Stephanopoulos N
3 Biotech
. 2019 Nov;
9(12):442.
PMID: 31763120
In the present study, leaves from 39 phylogenetically distant plant species were sampled and screened for asparaginyl endopeptidase ligase activity using mass spectrometry to test the generality of peptide ligases...