Alessia Ruggiero
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Explore the profile of Alessia Ruggiero including associated specialties, affiliations and a list of published articles.
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96
Citations
1202
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Recent Articles
1.
Romano M, Falchi F, De Gregorio E, Stabile M, Migliaccio A, Ruggiero A, et al.
Front Microbiol
. 2024 Dec;
15:1501051.
PMID: 39669780
Introduction: Antimicrobial-resistant pathogens are an ongoing threat to human and animal health. According to the World Health Organization (WHO), colistin is considered the last resort antibiotic against human infections due...
2.
Izzi G, Paladino A, Oliva R, Barra G, Ruggiero A, Del Vecchio P, et al.
Protein Sci
. 2024 Aug;
33(9):e5146.
PMID: 39150147
D2 is a structural and cooperative domain of Thermotoga maritima Arginine Binding Protein, that possesses a remarkable conformational stability, with a denaturation temperature of 102.6°C, at pH 7.4. The addition...
3.
Balasco N, Ruggiero A, Smaldone G, Pecoraro G, Coppola L, Pirone L, et al.
Int J Biol Macromol
. 2024 Aug;
277(Pt 4):134390.
PMID: 39111466
Members of the KCTD protein family play key roles in fundamental physio-pathological processes including cancer, neurodevelopmental/neuropsychiatric, and genetic diseases. Here, we report the crystal structure of the KCTD1 P20S mutant,...
4.
Berisio R, Barra G, Napolitano V, Privitera M, Romano M, Squeglia F, et al.
Biomolecules
. 2024 Apr;
14(4).
PMID: 38672487
Tuberculosis (TB) is the leading global cause of death f rom an infectious bacterial agent. Therefore, limiting its epidemic spread is a pressing global health priority. The chaperone-like protein HtpG...
5.
Maciejewska B, Squeglia F, Latka A, Privitera M, Olejniczak S, Switala P, et al.
mBio
. 2023 Sep;
14(5):e0132923.
PMID: 37707438
In this work, we determined the structure of phage KP34p57 capsular depolymerase and dissected the role of individual domains in trimerization and functional activity. The crystal structure serendipitously revealed that...
6.
Berisio R, Ruggiero A
Biomolecules
. 2023 Aug;
13(8).
PMID: 37627265
Tuberculosis (TB) remains one of the main causes of death by infection, especially in immunocompromised patients [...].
7.
Perrotta M, Lucibelli F, Mazzucchiello S, Fucci N, Mele B, Giordano E, et al.
Insects
. 2023 Jul;
14(7).
PMID: 37504611
In the model system for genetics, , sexual differentiation and male courtship behavior are controlled by sex-specific splicing of () and (). In vitro and in vivo studies showed that...
8.
Unveiling CD59-Antibody Interactions to Design Paratope-Mimicking Peptides for Complement Modulation
Sandomenico A, Ruggiero A, Iaccarino E, Oliver A, Squeglia F, Moreira M, et al.
Int J Mol Sci
. 2023 May;
24(10).
PMID: 37239905
CD59 is an abundant immuno-regulatory human protein that protects cells from damage by inhibiting the complement system. CD59 inhibits the assembly of the Membrane Attack Complex (MAC), the bactericidal pore-forming...
9.
Smaldone G, Pecoraro G, Pane K, Franzese M, Ruggiero A, Vitagliano L, et al.
Biology (Basel)
. 2023 Mar;
12(3).
PMID: 36979172
The KCTD protein family is traditionally regarded as proteins that play key roles in neurological physiopathology. However, new studies are increasingly demonstrating their involvement in many other biological processes, including...
10.
Romano M, Squeglia F, Kramarska E, Barra G, Choi H, Kim H, et al.
Cells
. 2023 Jan;
12(2).
PMID: 36672252
Tuberculosis (TB) is still the leading global cause of death from an infectious bacterial agent. Limiting tuberculosis epidemic spread is therefore an urgent global public health priority. As stated by...