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Alessandro Tocchio

Explore the profile of Alessandro Tocchio including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 421
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Recent Articles
1.
Mariniello M, Ghilli M, Favati B, Gerges I, Colizzi L, Tamplenizza M, et al.
Breast Cancer . 2023 Mar; 30(4):559-569. PMID: 36977972
Background: Based on the volume of tissue removed, conservative surgery (BCS) cannot always guarantee satisfactory cosmetic results, unless resorting to more complex oncoplastic approaches. Investigating an alternative to optimize aesthetic...
2.
Catelli E, Li Z, Sciutto G, Oliveri P, Prati S, Occhipinti M, et al.
Anal Chim Acta . 2023 Jan; 1239:340710. PMID: 36628716
The new challenge in the investigation of cultural heritage is the possibility to obtain stratigraphical information about the distribution of the different organic and inorganic components without sampling. In this...
3.
Gerges I, Tamplenizza M, Martello F, Koman S, Chincarini G, Recordati C, et al.
Sci Rep . 2021 Jun; 11(1):13310. PMID: 34172806
The use of cell-free scaffolds for the regeneration of clinically relevant volumes of soft tissue has been challenged, particularly in the case of synthetic biomaterials, by the difficulty of reconciling...
4.
El Assal R, Abou-Elkacem L, Tocchio A, Pasley S, Matosevic S, Kaplan D, et al.
Adv Sci (Weinh) . 2019 Apr; 6(6):1802045. PMID: 30937270
The ability to cryopreserve natural killer (NK) cells has a significant potential in modern cancer immunotherapy. Current cryopreservation protocols cause deterioration in NK cell viability and functionality. This work reports...
5.
Ren T, Grosshauser B, Sridhar K, Nieland T, Tocchio A, Schepers U, et al.
Biomaterials . 2019 Jan; 197:171-181. PMID: 30660993
The replication of the complex structure and three dimensional (3-D) interconnectivity of neurons in the brain is a great challenge. A few 3-D neuronal patterning approaches have been developed to...
6.
Canadas R, Ren T, Tocchio A, Marques A, Oliveira J, Reis R, et al.
Biomaterials . 2018 Aug; 181:402-414. PMID: 30138793
Organized networks are common in nature showing specific tissue micro-architecture, where cells can be found isotropically or anisotropically distributed in characteristic arrangements and tissue stiffness. However, when addressing an in...
7.
Rossi E, Guerrero J, Aprile P, Tocchio A, Kappos E, Gerges I, et al.
Acta Biomater . 2018 Apr; 73:154-166. PMID: 29684623
Statement Of Significance: In this study we combined the functionalities of a synthetic polymer with those of an engineered and subsequently devitalized extracellular matrix (ECM) to generate a hybrid material...
8.
Gerges I, Tamplenizza M, Martello F, Recordati C, Martelli C, Ottobrini L, et al.
Acta Biomater . 2018 Apr; 73:141-153. PMID: 29654992
Statement Of Significance: Exploring the potential of polyurethane-based soft foam as cell-free scaffold for soft tissue regeneration. In this work, we address the unmet need for synthetic functional soft tissue...
9.
Tocchio A, Durmus N, Sridhar K, Mani V, Coskun B, El Assal R, et al.
Adv Mater . 2017 Dec; 30(4). PMID: 29215164
In nature, cells self-assemble at the microscale into complex functional configurations. This mechanism is increasingly exploited to assemble biofidelic biological systems in vitro. However, precise coding of 3D multicellular living...
10.
Giwa S, Lewis J, Alvarez L, Langer R, Roth A, Church G, et al.
Nat Biotechnol . 2017 Jun; 35(6):530-542. PMID: 28591112
The ability to replace organs and tissues on demand could save or improve millions of lives each year globally and create public health benefits on par with curing cancer. Unmet...