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Alessandra Pacini

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Articles 66
Citations 1136
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Recent Articles
11.
Micheli L, Testai L, Angeli A, Carrino D, Pacini A, Margiotta F, et al.
Int J Mol Sci . 2022 Jun; 23(11). PMID: 35682907
Neuropathy development is a major dose-limiting side effect of anticancer treatments that significantly reduces patient's quality of life. The inadequate pharmacological approaches for neuropathic pain management warrant the identification of...
12.
Branca J, Carrino D, Paternostro F, Morucci G, Fiorillo C, Nicoletti C, et al.
Cells . 2022 May; 11(10). PMID: 35626683
Cadmium (Cd) is a well-known occupational and environmental pollutant worldwide, and its toxicity is widely recognised. Cd is reported to increase the permeability of the blood-brain barrier (BBB) and to...
13.
Micheli L, Parisio C, Lucarini E, Carrino D, Ciampi C, Toti A, et al.
Biomed Pharmacother . 2022 Feb; 148:112693. PMID: 35149388
The term tendinopathy indicates a wide spectrum of conditions characterized by alterations in tendon tissue homeostatic response and damage to the extracellular matrix. The current pharmacological approach involves the use...
14.
Branca J, Lascialfari Bruschi A, Pilia A, Carrino D, Guarnieri G, Gulisano M, et al.
Medicina (Kaunas) . 2022 Jan; 58(1). PMID: 35056445
: The "classic" thyroid gland arterial vascularization takes into account two superior thyroid arteries (STA), two inferior thyroid arteries (ITA) and, occasionally, a thyroid ima artery (TIMA). The present review...
15.
Branca J, Carrino D, Paternostro F, Gulisano M, Becatti M, Di Cesare Mannelli L, et al.
Eur J Histochem . 2021 Nov; 65(s1). PMID: 34755507
Oxaliplatin is a third-generation chemotherapy drug mainly used for colorectal cancer treatment. However, it is also known to trigger neuropathy whose underlying neurobiological mechanisms are still under investigation and currently...
16.
Lucarini E, Nocentini A, Bonardi A, Chiaramonte N, Parisio C, Micheli L, et al.
Cells . 2021 Oct; 10(10). PMID: 34685520
Persistent pain affecting patients with inflammatory bowel diseases (IBDs) is still very difficult to treat. Carbonic anhydrase (CA) represents an intriguing pharmacological target considering the anti-hyperalgesic efficacy displayed by CA...
17.
Micheli L, Parisio C, Lucarini E, Vona A, Toti A, Pacini A, et al.
J Exp Clin Cancer Res . 2021 Oct; 40(1):320. PMID: 34649573
Background: Neuropathic pain is a clinically relevant adverse effect of several anticancer drugs that markedly impairs patients' quality of life and frequently leads to dose reduction or therapy discontinuation. The...
18.
Lucarini E, Di Pilato V, Parisio C, Micheli L, Toti A, Pacini A, et al.
Pain . 2021 Aug; 163(5):861-877. PMID: 34393197
Recent findings linked gastrointestinal disorders characterized by abdominal pain to gut microbiota composition. The present work aimed to evaluate the power of gut microbiota as a visceral pain modulator and,...
19.
Micheli L, Rajagopalan R, Lucarini E, Toti A, Parisio C, Carrino D, et al.
Neurotherapeutics . 2021 Jul; 18(3):2008-2020. PMID: 34312766
Chemotherapy-induced neuropathy (CIN) is a major dose-limiting side effect of anticancer therapy that can compel therapy discontinuation. Inadequate analgesic efficacy of current pharmacological approaches requires the identification of innovative therapeutics...
20.
Branca J, Carrino D, Gulisano M, Ghelardini C, Di Cesare Mannelli L, Pacini A
Front Mol Biosci . 2021 May; 8:643824. PMID: 34026827
In the most recent decades, oxaliplatin has been used as a chemotherapeutic agent for colorectal cancer and other malignancies as well. Oxaliplatin interferes with tumor growth predominantly exerting its action...