Alessandra Montecucco
Overview
Explore the profile of Alessandra Montecucco including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
703
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Recent Articles
1.
Capanni C, Schena E, Di Giampietro M, Montecucco A, Mattioli E, Lattanzi G
Front Cell Dev Biol
. 2022 Dec;
10:1018102.
PMID: 36467410
Lamin A is a main constituent of the nuclear lamina and contributes to nuclear shaping, mechano-signaling transduction and gene regulation, thus affecting major cellular processes such as cell cycle progression...
2.
Giordano M, Infantino L, Biggiogera M, Montecucco A, Biamonti G
Int J Mol Sci
. 2020 Apr;
21(8).
PMID: 32316575
Heat shock activates the transcription of arrays of Satellite III (SatIII) DNA repeats in the pericentromeric heterochromatic domains of specific human chromosomes, the longest of which is on chromosome 9....
3.
Biamonti G, Maita L, Montecucco A
Front Oncol
. 2018 Oct;
8:408.
PMID: 30319972
Alternative splicing is a pervasive mechanism that molds the transcriptome to meet cell and organism needs. However, how this layer of gene expression regulation is coordinated with other aspects of...
4.
Magni M, Buscemi G, Maita L, Peng L, Chan S, Montecucco A, et al.
Cell Death Differ
. 2018 Jul;
26(5):918-931.
PMID: 30050056
Protein acetylation and deacetylation events are finely regulated by lysine-acetyl-transferases and lysine-deacetylases and constitute an important tool for the activation or inhibition of specific cellular pathways. One of the most...
5.
Pignataro D, Francia S, Zanetta F, Brenna G, Brandini S, Olivieri A, et al.
Sci Rep
. 2017 Aug;
7(1):9528.
PMID: 28842646
Genome integrity is continuously threatened by endogenous sources of DNA damage including reactive oxygen species (ROS) produced by cell metabolism. Factors of the RNA interference (RNAi) machinery have been recently...
6.
7.
Montecucco A, Zanetta F, Biamonti G
EXCLI J
. 2015 Nov;
14:95-108.
PMID: 26600742
Etoposide derives from podophyllotoxin, a toxin found in the American Mayapple. It was first synthesized in 1966 and approved for cancer therapy in 1983 by the U.S. Food and Drug...
8.
Cremaschi P, Oliverio M, Leva V, Bione S, Carriero R, Mazzucco G, et al.
PLoS One
. 2015 Jul;
10(7):e0130561.
PMID: 26151554
Moderate DNA damage resulting from metabolic activities or sub-lethal doses of exogenous insults may eventually lead to cancer onset. Human 46BR.1G1 cells bear a mutation in replicative DNA ligase I...
9.
Biamonti G, Catillo M, Pignataro D, Montecucco A, Ghigna C
Semin Cell Dev Biol
. 2014 Mar;
32:30-6.
PMID: 24657195
Alternative splicing emerges as a potent and pervasive mechanism of gene expression regulation that expands the coding capacity of the genome and forms an intermediate layer of regulation between transcriptional...
10.
Cremaschi P, Rovida S, Sacchi L, Lisa A, Calvi F, Montecucco A, et al.
BMC Bioinformatics
. 2014 Feb;
15 Suppl 1:S6.
PMID: 24564370
Background: The amount of gene expression data available in public repositories has grown exponentially in the last years, now requiring new data mining tools to transform them in information easily...