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Alessandra Manca

Explore the profile of Alessandra Manca including associated specialties, affiliations and a list of published articles. Areas
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Articles 75
Citations 698
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Recent Articles
11.
Cusato J, Manca A, Palermiti A, Mula J, Avataneo V, Antonucci M, et al.
Int J Antimicrob Agents . 2024 Mar; 63(6):107137. PMID: 38508536
Objectives: Blood-brain barrier impairment is frequent in people living with human immunodeficiency virus (PLWHIV), affecting the penetration of target cells and antiretrovirals into the central nervous system, through transporters (e.g....
12.
Diedenhofen G, Morgia A, Sinnona N, Pacchiarotti A, Fiaschetti A, Forte V, et al.
Ann Ig . 2024 Mar; 36(5):537-548. PMID: 38465396
Background: Colorectal cancer currently presents the third-highest incidence of cancers worldwide, making secondary prevention through screening programs for colorectal cancer, usually by Fecal Occult Blood Testing, an essential preventive medicine...
13.
Cusato J, Cafasso C, Antonucci M, Palermiti A, Manca A, Caviglia G, et al.
Biomedicines . 2024 Feb; 12(2). PMID: 38397922
Although the role of vitamin D (VD) in the pathogenesis and progression of Crohn's disease (CD) is known, the association between single-nucleotide polymorphisms (SNPs) of genes linked to vitamin D...
14.
Manca A, Palermiti A, Mula J, Cusato J, Maiese D, Simiele M, et al.
Pharmaceutics . 2023 Sep; 15(9). PMID: 37765315
Background: Fosfomycin acts against aerobic Gram-/+ bacteria by blocking the synthesis of peptidoglycan. Its use has been currently re-evaluated for intravenous administration for the treatment of systemic infections by multidrug-resistant...
15.
Dore M, Fanciulli G, Manca A, Pes G
J Clin Med . 2023 Aug; 12(15). PMID: 37568552
Background: infection has been associated with an increased risk of thyroid diseases (TDs), although scientific evidence is conflicting. In the present study the relationship between TDs, including both autoimmune (AI)...
16.
Fois P, Mureddu L, Manca A, Varrucciu S, Crescio C, Gallus R, et al.
J Pers Med . 2023 Jul; 13(7). PMID: 37511688
(1) Background: Warthin tumors account for about 20% of all benign salivary tumors, approaching 50% if we consider only the parotid gland. Wait and see is considered a reasonable option,...
17.
Manca A, Mula J, Palermiti A, Vischia F, De Cori D, Venturello S, et al.
Biomed Pharmacother . 2023 Jul; 165:115103. PMID: 37413901
Schizophrenia affects approximately 24 million people worldwide and clozapine is the most effective antipsychotic drug. Nevertheless, its use in therapy is limited due to adverse effects.Therapeutic drug monitoring is a...
18.
Manca A, De Nicolo A, Vivo E, Ferrara M, Oh S, Khalili S, et al.
Pharmaceuticals (Basel) . 2023 Jun; 16(6). PMID: 37375850
Background: Opioids are considered the cornerstone of pain management: they show good efficacy as a first-line therapy for moderate to severe cancer pain. Since pharmacokinetic/pharmacodynamic information about the tissue-specific effect...
19.
Cusato J, Manca A, Palermiti A, Mula J, Costanzo M, Antonucci M, et al.
Biomedicines . 2023 May; 11(5). PMID: 37239131
Background: COVID-19 is characterized by an uncontrolled inflammatory response with high pro-inflammatory cytokine production through the activation of intracellular pathways, such as mitogen-activated protein kinase (MAPK). Viruses are able to...
20.
Cusato J, Manca A, Palermiti A, Mula J, Costanzo M, Antonucci M, et al.
Antioxidants (Basel) . 2023 May; 12(5). PMID: 37237997
An uncontrolled inflammatory response during SARS-CoV-2 infection has been highlighted in several studies. This seems to be due to pro-inflammatory cytokines whose production could be regulated by vitamin D, ROS...