Alessandra Fiorio Pla
Overview
Explore the profile of Alessandra Fiorio Pla including associated specialties, affiliations and a list of published articles.
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49
Citations
886
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Recent Articles
11.
Grolez G, Chinigo G, Barras A, Hammadi M, Noyer L, Kondratska K, et al.
Int J Mol Sci
. 2022 Jun;
23(12).
PMID: 35743115
In the fight against prostate cancer (PCa), TRPM8 is one of the most promising clinical targets. Indeed, several studies have highlighted that TRPM8 involvement is key in PCa progression because...
12.
Scarpellino G, Genova T, Quarta E, Distasi C, Dionisi M, Fiorio Pla A, et al.
Cancers (Basel)
. 2022 Jun;
14(11).
PMID: 35681724
The tumoral microenvironment often displays peculiar features, including accumulation of extracellular ATP, hypoxia, low pH-acidosis, as well as an imbalance in zinc (Zn) and calcium (Ca). We previously reported the...
13.
Butnarasu C, Petrini P, Bracotti F, Visai L, Guagliano G, Fiorio Pla A, et al.
Adv Healthc Mater
. 2022 May;
11(15):e2200340.
PMID: 35608152
Mucus is a complex barrier for pharmacological treatments and overcoming it is one of the major challenges faced during transmucosal drug delivery. To tackle this issue, a novel class of...
14.
Chinigo G, Grolez G, Audero M, Bokhobza A, Bernardini M, Cicero J, et al.
Cancers (Basel)
. 2022 May;
14(9).
PMID: 35565390
Emerging evidence indicates that the TRPM8 channel plays an important role in prostate cancer (PCa) progression, by impairing the motility of these cancer cells. Here, we reveal a novel facet...
15.
Chinigo G, Gonzalez-Paredes A, Gilardino A, Barbero N, Barolo C, Gasco P, et al.
Spectrochim Acta A Mol Biomol Spectrosc
. 2022 Jan;
271:120909.
PMID: 35093822
Polymethine dyes (PMD) have proved to be excellent candidates in the biomedical field for potential applications in both diagnostic and therapeutic. However, PMD application in biomedicine is hindered by their...
16.
Villari G, Enrico Bena C, Del Giudice M, Gioelli N, Sandri C, Camillo C, et al.
EMBO J
. 2020 Nov;
39(24):e103661.
PMID: 33215754
Although subcellular positioning of endosomes significantly impacts on their functions, the molecular mechanisms governing the different steady-state distribution of early endosomes (EEs) and late endosomes (LEs)/lysosomes (LYs) in peripheral and...
17.
Chinigo G, Fiorio Pla A, Gkika D
Front Pharmacol
. 2020 Nov;
11:581455.
PMID: 33132914
Transient Receptor Potential (TRP) cations channels, as key regulators of intracellular calcium homeostasis, play a central role in the essential hallmarks of cancer. Among the multiple pathways in which TRPs...
18.
Scarpellino G, Munaron L, Cantelmo A, Fiorio Pla A
Rev Physiol Biochem Pharmacol
. 2020 Aug;
182:111-137.
PMID: 32809072
Calcium (Ca)-permeable channels are key players in different processes leading to blood vessel formation via sprouting angiogenesis, including endothelial cell (EC) proliferation and migration, as well as in controlling vascular...
19.
Brossa A, Buono L, Fallo S, Fiorio Pla A, Munaron L, Bussolati B
Int J Mol Sci
. 2019 Dec;
20(24).
PMID: 31817884
Endothelial cells present in tumors show different origin, phenotype, and genotype with respect to the normal counterpart. Various mechanisms of intra-tumor vasculogenesis sustain the complexity of tumor vasculature, which can...
20.
Bernardini M, Brossa A, Chinigo G, Grolez G, Trimaglio G, Allart L, et al.
Cancers (Basel)
. 2019 Jul;
11(7).
PMID: 31288452
: Transient receptor potential (TRP) channels control multiple processes involved in cancer progression by modulating cell proliferation, survival, invasion and intravasation, as well as, endothelial cell (EC) biology and tumor...