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Alessandra Apicella

Explore the profile of Alessandra Apicella including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 48
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Recent Articles
1.
Apicella A, Heunemann P, Dejace L, Marascio M, Plummer C, Fischer P
Colloids Surf B Biointerfaces . 2017 May; 156:221-226. PMID: 28531879
Periodontitis affects the attachment of natural teeth, and infection or inflammation associated with periodontitis may affect peri-implant tissues. Enamel matrix derivative (EMD) proteins provide stimulation for self-regeneration of the damaged...
2.
Apicella A, Marascio M, Colangelo V, Soncini M, Gautieri A, Plummer C
J Biomol Struct Dyn . 2016 Jul; 35(8):1813-1823. PMID: 27366858
Amelogenin refers to a class of intrinsically disordered proteins that are the major constituents of enamel matrix derivative (EMD), an extract of porcine fetal teeth used in regenerative periodontal therapy....
3.
Apicella A, Heunemann P, Bolisetty S, Marascio M, Gemperli Graf A, Garamszegi L, et al.
PLoS One . 2015 Dec; 10(12):e0144641. PMID: 26670810
In a current procedure for periodontal tissue regeneration, enamel matrix derivative (EMD), which is the active component, is mixed with a propylene glycol alginate (PGA) gel carrier and applied directly...
4.
Apicella A, Soncini M, Deriu M, Natalello A, Bonanomi M, Dellasega D, et al.
PLoS One . 2013 Mar; 8(3):e58794. PMID: 23527026
Protein misfolding and aggregation in intracellular and extracellular spaces is regarded as a main marker of the presence of degenerative disorders such as amyloidoses. To elucidate the mechanisms of protein...
5.
Apicella A, Natalello A, Frana A, Baserga A, Casari C, Bottani C, et al.
Biochimie . 2012 Jan; 94(4):1026-31. PMID: 22234302
Ataxin-3 (AT3) triggers spinocerebellar ataxia type 3 when it carries a polyglutamine stretch expanded beyond a critical threshold. By Fourier transform infrared spectroscopy and atomic force microscopy we previously showed...
6.
Natalello A, Frana A, Relini A, Apicella A, Invernizzi G, Casari C, et al.
PLoS One . 2011 May; 6(4):e18789. PMID: 21533208
The protein ataxin-3 consists of an N-terminal globular Josephin domain (JD) and an unstructured C-terminal region containing a stretch of consecutive glutamines that triggers the neurodegenerative disorder spinocerebellar ataxia type...