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Alessandra Affinito

Explore the profile of Alessandra Affinito including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 541
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Recent Articles
1.
Quintavalle C, Ingenito F, Roscigno G, Pattanayak B, Esposito C, Affinito A, et al.
Cell Death Discov . 2025 Mar; 11(1):94. PMID: 40069570
The tumor microenvironment profoundly influences tumor complexity, particularly in breast cancer, where cancer-associated fibroblasts play pivotal roles in tumor progression and therapy resistance. Extracellular vesicles are involved in mediating communication...
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Roscigno G, Affinito A, Quintavalle C, Cillari R, Condorelli G, Cavallaro G, et al.
ACS Biomater Sci Eng . 2024 Jun; 10(7):4269-4278. PMID: 38916153
This study investigates the remarkable attributes of sulfur-doped carbon nanodots (CDs) synthesized in high yield and a narrow size distribution (4.8 nm). These CDs exhibit notable features, including potential bioelimination...
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Affinito A, Quintavalle C, Chianese R, Roscigno G, Fiore D, DArgenio V, et al.
Cell Death Discov . 2024 Mar; 10(1):140. PMID: 38485929
Multiple oncogenic alterations contribute to breast cancer development. Metabolic reprogramming, deeply contributing to tumor microenvironment (TME) education, is now widely recognized as a hallmark of cancer. The reverse Warburg effect...
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Nuzzo S, Iaboni M, Ibba M, Rienzo A, Musumeci D, Franzese M, et al.
Front Mol Biosci . 2022 Oct; 9:956935. PMID: 36188221
Hypoxia plays a crucial role in tumorigenesis and drug resistance, and it is recognised as a major factor affecting patient clinical outcome. Therefore, the detection of hypoxic areas within the...
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Scognamiglio I, Cocca L, Puoti I, Palma F, Ingenito F, Quintavalle C, et al.
Mol Ther Nucleic Acids . 2022 Sep; 29:656. PMID: 36090750
[This corrects the article DOI: 10.1016/j.omtn.2022.02.013.].
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Pane K, Quintavalle C, Nuzzo S, Ingenito F, Roscigno G, Affinito A, et al.
Int J Mol Sci . 2022 Apr; 23(7). PMID: 35409352
Extracellular vesicles (EVs) shuttle proteins, RNA, DNA, and lipids crucial for cell-to-cell communication. Recent findings have highlighted that EVs, by virtue of their cargo, may also contribute to breast cancer...
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Scognamiglio I, Cocca L, Puoti I, Palma F, Ingenito F, Quintavalle C, et al.
Mol Ther Nucleic Acids . 2022 Mar; 28:17-31. PMID: 35317202
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype. TNBC progression is sustained by recruitment of a strong tumor microenvironment (TME) mainly composed of cancer-associated fibroblasts (CAFs) able...
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Roscigno G, Quintavalle C, Biondi-Zoccai G, De Micco F, Frati G, Affinito A, et al.
J Am Coll Cardiol . 2021 May; 77(21):2667-2676. PMID: 34045024
Background: Administration of iodinated contrast medium (CM) during invasive cardiovascular procedures may be associated with impairment of kidney function. Objectives: Urinary dickkopf-3 (DKK3), a stress-induced renal tubular epithelium-derived glycoprotein, has...
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Palma F, Affinito A, Nuzzo S, Roscigno G, Scognamiglio I, Ingenito F, et al.
Cancer Gene Ther . 2020 Sep; 28(5):413-426. PMID: 32948832
Lung cancer is still the leading cause of death by cancer worldwide despite advances both in its detection and therapy. Multiple oncogenic driver alterations have been discovered, opening the prospective...