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Alenka Smid

Explore the profile of Alenka Smid including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 133
Followers 0
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Recent Articles
1.
Blagojevic M, Zupanc M, Gostisa J, Stres B, Smid A, Dular M, et al.
Ultrason Sonochem . 2025 Feb; 115:107291. PMID: 40020275
In this study, laboratory-scale Pinned Disc Rotary Generator of Hydrodynamic Cavitation was used to treat waste-activated sludge with a Total Solids concentration of 0.7 %. Five different rotor-stator arrangements were...
2.
Urbancic D, Jukic M, Smid A, Gobec S, Jazbec J, Mlinaric-Rascan I
Biomed Pharmacother . 2025 Feb; 184:117893. PMID: 39923408
Understanding the molecular mechanisms of medicines is crucial for developing novel drugs, for repurposing existing medicines, and for predicting toxicities. Thiopurine S-methyltransferase (TPMT) serves as an exemplary case in personalized...
3.
Kuzelicki N, Smid A, Vidmar Golja M, Kek T, Eberlinc A, Gersak B, et al.
Birth Defects Res . 2024 Oct; 116(11):e2408. PMID: 39473220
Background: Uninterrupted folate metabolism plays a vital role in embryonic development, ensuring a supply of one-carbon-activated folate cofactors for essential processes. Folate deficiency has been implicated in the development of...
4.
Smid A, Urbancic D, Zlajpah J, Stollarova N, Prelog T, Kavcic M, et al.
Pharmacogenomics . 2024 Oct; 25(12-13):515-525. PMID: 39453028
Determining variant alleles to predict patient response to thiopurine therapy represents one of the first successful implementations of pharmacogenomics in clinical practice. However, despite the -adjusted thiopurine dosing, some wild-type...
5.
Urbancic D, Pasha F, Smid A, Mlinaric-Rascan I
Acta Pharm . 2024 Sep; 74(3):355-381. PMID: 39279525
Despite great therapeutic advances in the field of biologics, small synthetic molecules such as thiopurines, including azathioprine, mercaptopurine, and thioguanine, remain an important therapeutic pillar in the treatment of inflammatory...
6.
Smid A, Stajdohar M, Milek M, Urbancic D, Kuzelicki N, Tamm R, et al.
Eur J Pharm Sci . 2023 Oct; 192:106616. PMID: 37865284
Thiopurine S-methyltransferase (TPMT) is an important enzyme involved in the deactivation of thiopurines and represents a major determinant of thiopurine-related toxicities. Despite its well-known importance in thiopurine metabolism, the understanding...
7.
Kuzelicki N, Smid A, Vidmar Golja M, Kek T, Gersak B, Mazic U, et al.
J Cardiovasc Dev Dis . 2022 Jun; 9(6). PMID: 35735795
Several environmental and genetic factors may influence the risk of congenital heart defects (CHDs), which can have a substantial impact on pediatric morbidity and mortality. We investigated the association of...
8.
Rajh E, Sket T, Praznik A, Susjan P, Smid A, Urbancic D, et al.
Molecules . 2021 Nov; 26(21). PMID: 34771026
Early diagnosis with rapid detection of the virus plays a key role in preventing the spread of infection and in treating patients effectively. In order to address the need for...
9.
Grzelj J, Marovt M, Marko P, Mlinaric-Rascan I, Gmeiner T, Smid A
Medicina (Kaunas) . 2021 Oct; 57(10). PMID: 34684087
: Methotrexate is widely prescribed for the treatment of moderate-to-severe psoriasis. As drug survival encompasses efficacy, safety, and treatment satisfaction, such studies provide insights into successful drug treatments in the...
10.
Zeckanovic A, Kavcic M, Prelog T, Smid A, Jazbec J
Nutrients . 2021 Apr; 13(4). PMID: 33810451
A major problem of oral iron supplementation efficacy in children is its tolerability and compliance. We aimed to determine the safety and efficacy of a novel food supplement >Your< Iron...