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Aleksey Y Domozhirov

Explore the profile of Aleksey Y Domozhirov including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Shivshankar P, Mueller-Ortiz S, Domozhirov A, Bi W, Collum S, Doursout M, et al.
Respir Res . 2025 Feb; 26(1):68. PMID: 40016722
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced coronavirus disease 2019 (COVID-19) pandemic has challenged the current understanding of the complement cascade mechanisms of host immune responses during infection-induced nonresolvable...
2.
Simmons K, Mazzilli J, Mueller-Ortiz S, Domozhirov A, Garcia C, Zsigmond E, et al.
Mol Immunol . 2019 Dec; 118:91-98. PMID: 31862673
The purpose of this study was to identify a membrane-bound complement inhibitor that could be overexpressed on retinal pigment epithelial cells (RPE) providing a potential therapy for age-related macular degeneration...
3.
Mazzilli J, Snook J, Simmons K, Domozhirov A, Garcia C, Wetsel R, et al.
J Ocul Pharmacol Ther . 2019 Oct; 36(1):65-69. PMID: 31596637
Age-related macular degeneration (AMD) is a common disease trending towards epidemic proportions and is a leading cause of irreversible vision loss in people over the age of 65. A pathomechanism...
4.
Domozhirov A, Mazzilli J, Wetsel R, Zsigmond E
Stem Cell Res . 2019 Jul; 39:101508. PMID: 31357114
Monosomy of chromosome X is associated with high prenatal mortality of female embryos and severe developmental abnormalities of patients born with Turner's syndrome (45,XO). The CDMLe012-A-1 human embryonic stem cell...
5.
Mazzilli J, Domozhirov A, Mueller-Ortiz S, Garcia C, Wetsel R, Zsigmond E
Stem Cell Res . 2017 Apr; 18:37-40. PMID: 28395800
The CR-4 human embryonic stem cell line was derived from the inner cell mass of a developing blastocyst. This cell line has been adapted to grow in feeder-free conditions and...