Aleksander L Sieron
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Explore the profile of Aleksander L Sieron including associated specialties, affiliations and a list of published articles.
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61
Citations
435
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Recent Articles
1.
Krakowian D, Lesiak M, Augusciak-Duma A, Witecka J, Kusz D, Sieron A, et al.
Cells
. 2024 Jun;
13(12.
PMID: 38920651
Bone formation is a complex process regulated by a variety of pathways that are not yet fully understood. One of the proteins involved in multiple osteogenic pathways is TID (DNAJA3)....
2.
Botor M, Augusciak-Duma A, Lesiak M, Sieron L, Dziedzic-Kowalska A, Witecka J, et al.
Pharmaceuticals (Basel)
. 2023 Oct;
16(10).
PMID: 37895885
() is a group of connective tissue disorders leading to abnormal bone formation, mainly due to mutations in genes encoding collagen type I (Col I). Osteogenesis is regulated by a...
3.
Fus-Kujawa A, Mendrek B, Bajdak-Rusinek K, Diak N, Strzelec K, Gutmajster E, et al.
Front Bioeng Biotechnol
. 2023 Jul;
11:1205122.
PMID: 37456734
The benefits of patient's specific cell/gene therapy have been reported in relation to numerous genetic related disorders including osteogenesis imperfecta (OI). In osteogenesis imperfecta particularly also a drug therapy based...
4.
Botor M, Fus-Kujawa A, Uroczynska M, Stepien K, Galicka A, Gawron K, et al.
Biomolecules
. 2021 Oct;
11(10).
PMID: 34680126
Osteogenesis Imperfecta (OI) is a group of connective tissue disorders with a broad range of phenotypes characterized primarily by bone fragility. The prevalence of OI ranges from about 1:15,000 to...
5.
Augusciak-Duma A, Lesiak M, Stepien K, Gutmajster E, Sieron A
Acta Biochim Pol
. 2021 Oct;
68(4):745-750.
PMID: 34669362
Abdominal aortic aneurysm is a process involving the disruption and reconstruction of the extracellular matrix and the apoptosis of smooth muscle cells under the strong influence of the immune system....
6.
Fus-Kujawa A, Prus P, Bajdak-Rusinek K, Teper P, Gawron K, Kowalczuk A, et al.
Front Bioeng Biotechnol
. 2021 Aug;
9:701031.
PMID: 34354988
Transfection is a powerful analytical tool enabling studies of gene products and functions in eukaryotic cells. Successful delivery of genetic material into cells depends on DNA quantity and quality, incubation...
7.
Augusciak-Duma A, Stepien K, Lesiak M, Gutmajster E, Fus-Kujawa A, Botor M, et al.
J Appl Genet
. 2021 Jun;
62(3):499-506.
PMID: 34091862
Abdominal aortic aneurysm refers to abnormal, asymmetric distension of the infrarenal aortic wall due to pathological remodelling of the extracellular matrix. The distribution of enzymes remodelling the extracellular matrix and...
8.
Lesiak M, Augusciak-Duma A, Stepien K, Fus-Kujawa A, Botor M, Sieron A
J Appl Genet
. 2021 Jun;
62(3):487-497.
PMID: 34080122
The aim of the study was to investigate specific potential markers for cells obtained from three layers of human AAA divided into three segments along the AAA based on morphological...
9.
Fus-Kujawa A, Mendrek B, Trybus A, Bajdak-Rusinek K, Stepien K, Sieron A
Biomolecules
. 2021 Jun;
11(5).
PMID: 34067183
Induced pluripotent stem cells (iPSCs) are defined as reprogrammed somatic cells exhibiting embryonic stem cell characteristics. Since their discovery in 2006, efforts have been made to utilize iPSCs in clinical...
10.
Mendrek B, Fus-Kujawa A, Teper P, Botor M, Kubacki J, Sieron A, et al.
Int J Pharm
. 2020 Aug;
589:119823.
PMID: 32861771
We designed a novel thermoresponsive system of nanolayers composed of star poly[oligo(ethylene glycol) methacrylate]s (S-POEGMA) covalently bonded to a solid support and covered with polyplexes of cationic star polymers and...