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Alejandro Toledo-Arana

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Articles 49
Citations 2699
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Recent Articles
1.
Fernandez-Calvet A, Matilla-Cuenca L, Izco M, Navarro S, Serrano M, Ventura S, et al.
Nat Commun . 2024 May; 15(1):4150. PMID: 38755164
Age-related neurodegenerative diseases involving amyloid aggregation remain one of the biggest challenges of modern medicine. Alterations in the gastrointestinal microbiome play an active role in the aetiology of neurological disorders....
2.
Rapun-Araiz B, Sorzabal-Bellido I, Asensio-Lopez J, Lazaro-Diez M, Ariz M, Sobejano de la Merced C, et al.
Microbiol Spectr . 2023 Oct; 11(6):e0099323. PMID: 37795992
Genomic diversity of nontypeable strains confers phenotypic heterogeneity. Multiple strains of can be simultaneously isolated from clinical specimens, but we lack detailed information about polyclonal infection dynamics by this pathogen....
3.
Lai L, Villanueva M, Muruzabal-Galarza A, Fernandez A, Unzue A, Toledo-Arana A, et al.
Toxins (Basel) . 2023 Mar; 15(3). PMID: 36977103
is a species of mosquito, originally from Southeast Asia, that belongs to the Culicidae family and the Dipteran insect order. The distribution of this vector has rapidly changed over the...
4.
Matilla-Cuenca L, Taglialegna A, Gil C, Toledo-Arana A, Lasa I, Valle J
NPJ Biofilms Microbiomes . 2022 Jul; 8(1):62. PMID: 35909185
Biofilm engineering has emerged as a controllable way to fabricate living structures with programmable functionalities. The amyloidogenic proteins comprising the biofilms can be engineered to create self-assembling extracellular functionalized surfaces....
5.
Menendez-Gil P, Catalan-Moreno A, Caballero C, Toledo-Arana A
Front Microbiol . 2022 May; 13:838042. PMID: 35572681
Iron acquisition and modulation of its intracellular concentration are critical for the development of all living organisms. So far, several proteins have been described to be involved in iron homeostasis....
6.
Bastet L, Bustos-Sanmamed P, Catalan-Moreno A, Caballero C, Cuesta S, Matilla-Cuenca L, et al.
Int J Mol Sci . 2022 Jan; 23(1). PMID: 35009002
Bacterial genomes are pervasively transcribed, generating a wide variety of antisense RNAs (asRNAs). Many of them originate from transcriptional read-through events (TREs) during the transcription termination process. Previous transcriptome analyses...
7.
Desgranges E, Barrientos L, Herrgott L, Marzi S, Toledo-Arana A, Moreau K, et al.
Mol Microbiol . 2021 Nov; 117(1):193-214. PMID: 34783400
Staphylococcus aureus RsaG is a 3'-untranslated region (3'UTR) derived sRNA from the conserved uhpT gene encoding a glucose-6-phosphate (G6P) transporter expressed in response to extracellular G6P. The transcript uhpT-RsaG undergoes...
8.
Matilla-Cuenca L, Toledo-Arana A, Valle J
Antibiotics (Basel) . 2021 Jul; 10(7). PMID: 34210036
The choice of an effective therapeutic strategy in the treatment of biofilm-related infections is a significant issue. Amyloids, which have been historically related to human diseases, are now considered to...
9.
Fernandez-Calvet A, Euba B, Gil-Campillo C, Catalan-Moreno A, Moleres J, Marti S, et al.
mBio . 2021 Jun; 12(3):e0078921. PMID: 34154422
Genetic variants arising from within-patient evolution shed light on bacterial adaptation during chronic infection. Contingency loci generate high levels of genetic variation in bacterial genomes, enabling adaptation to the stringent...
10.
Catalan-Moreno A, Cela M, Menendez-Gil P, Irurzun N, Caballero C, Caldelari I, et al.
Nucleic Acids Res . 2021 Mar; 49(6):3409-3426. PMID: 33660769
Thermoregulation of virulence genes in bacterial pathogens is essential for environment-to-host transition. However, the mechanisms governing cold adaptation when outside the host remain poorly understood. Here, we found that the...