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Alejandro Chacon

Explore the profile of Alejandro Chacon including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 28
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Recent Articles
1.
Schmidt B, Kallenborn F, Chacon A, Hundt C
BMC Bioinformatics . 2024 Nov; 25(1):342. PMID: 39488701
Background: The maximal sensitivity for local pairwise alignment makes the Smith-Waterman algorithm a popular choice for protein sequence database search. However, its quadratic time complexity makes it compute-intensive. Unfortunately, current...
2.
Laurie S, Fernandez-Callejo M, Marco-Sola S, Trotta J, Camps J, Chacon A, et al.
Hum Mutat . 2016 Sep; 37(12):1263-1271. PMID: 27604516
As whole genome sequencing becomes cheaper and faster, it will progressively substitute targeted next-generation sequencing as standard practice in research and diagnostics. However, computing cost-performance ratio is not advancing at...
3.
Chacon A, Marco-Sola S, Espinosa A, Ribeca P, Moure J
IEEE/ACM Trans Comput Biol Bioinform . 2015 Oct; 12(5):1048-59. PMID: 26451818
The recent advent of high-throughput sequencing machines producing big amounts of short reads has boosted the interest in efficient string searching techniques. As of today, many mainstream sequence alignment software...