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Alejandro Barrallo-Gimeno

Explore the profile of Alejandro Barrallo-Gimeno including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 1694
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Recent Articles
1.
Gaitan-Penas H, Perez-Rius C, Muhaisen A, Castellanos A, Errasti-Murugarren E, Barrallo-Gimeno A, et al.
J Physiol . 2024 Jul; 602(16):3975-3994. PMID: 39031529
The function of the chloride channel ClC-1 is crucial for the control of muscle excitability. Thus, reduction of ClC-1 functions by CLCN1 mutations leads to myotonia congenita. Many different animal...
2.
Borrajo M, Sedano D, Palou A, Gimenez-Esbri V, Barrallo-Gimeno A, Llorens J
Front Cell Dev Biol . 2024 Jun; 12:1404894. PMID: 38895157
Vestibular sensory epithelia contain type I and type II sensory hair cells (HCI and HCII). Recent studies have revealed molecular markers for the identification of these cells, but the precise...
3.
Maroto A, Borrajo M, Prades S, Callejo A, Amilibia E, Perez-Grau M, et al.
Arch Toxicol . 2023 May; 97(7):1943-1961. PMID: 37195449
Hair cell (HC) loss by epithelial extrusion has been described to occur in the rodent vestibular system during chronic 3,3'-iminodipropionitrile (IDPN) ototoxicity. This is preceded by dismantlement of the calyceal...
4.
Greguske E, Maroto A, Borrajo M, Palou A, Gut M, Esteve-Codina A, et al.
Neurobiol Dis . 2023 Apr; 182:106134. PMID: 37100209
The vestibular ganglion contains primary sensory neurons that are postsynaptic to the transducing hair cells (HC) and project to the central nervous system. Understanding the response of these neurons to...
5.
Barrallo-Gimeno A, Llorens J
Front Cell Dev Biol . 2022 Dec; 10:1085225. PMID: 36582469
Hearing or balance loss are disabling conditions that have a serious impact in those suffering them, especially when they appear in children. Their ultimate cause is frequently the loss of...
6.
Maroto A, Barrallo-Gimeno A, Llorens J
Hear Res . 2021 Sep; 410:108336. PMID: 34481267
The tail-lift reflex and the air-righting reflex in rats are anti-gravity reflexes that depend on vestibular function. To begin identifying their cellular basis, this study examined the relationship between reflex...
7.
Perez-Rius C, Folgueira M, Elorza-Vidal X, Alia A, Hoegg-Beiler M, Eeza M, et al.
Orphanet J Rare Dis . 2019 Nov; 14(1):268. PMID: 31752924
Background: Megalencephalic Leukoencephalopathy with subcortical Cysts (MLC) is a rare type of leukodystrophy characterized by astrocyte and myelin vacuolization, epilepsy and early-onset macrocephaly. MLC is caused by mutations in MLC1...
8.
Perez-Rius C, Castellanos A, Gaitan-Penas H, Navarro A, Artuch R, Barrallo-Gimeno A, et al.
J Physiol . 2019 Jun; 597(15):3969-3983. PMID: 31177533
Key Points: We have characterized the zebrafish clc-k and barttin proteins, demonstrating that they form a protein complex mediating chloride flux in a similar manner to their mammalian counterparts. As...
9.
Estevez R, Elorza-Vidal X, Gaitan-Penas H, Perez-Rius C, Armand-Ugon M, Alonso-Gardon M, et al.
Eur J Med Genet . 2017 Oct; 61(1):50-60. PMID: 29079544
Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare type of leukodystrophy characterized by dysfunction of the role of glial cells in controlling brain fluid and ion homeostasis. Patients affected...
10.
Sirisi S, Elorza-Vidal X, Arnedo T, Armand-Ugon M, Callejo G, Capdevila-Nortes X, et al.
Hum Mol Genet . 2017 Apr; 26(13):2436-2450. PMID: 28398517
Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare type of leukodystrophy caused by mutations in either MLC1 or GLIALCAM. GlialCAM is necessary for the correct targeting of MLC1, but...