Alec Wysoker
Overview
Explore the profile of Alec Wysoker including associated specialties, affiliations and a list of published articles.
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14
Citations
33726
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Recent Articles
1.
Ling E, Nemesh J, Goldman M, Kamitaki N, Reed N, Handsaker R, et al.
Nature
. 2024 Mar;
627(8004):604-611.
PMID: 38448582
Human brains vary across people and over time; such variation is not yet understood in cellular terms. Here we describe a relationship between people's cortical neurons and cortical astrocytes. We...
2.
Ling E, Nemesh J, Goldman M, Kamitaki N, Reed N, Handsaker R, et al.
bioRxiv
. 2024 Jan;
PMID: 38260461
Human brains vary across people and over time; such variation is not yet understood in cellular terms. Here we describe a striking relationship between people's cortical neurons and cortical astrocytes....
3.
Del Rosario R, Krienen F, Zhang Q, Goldman M, Mello C, Lutservitz A, et al.
bioRxiv
. 2023 Oct;
PMID: 37904944
Chimerism happens rarely among most mammals but is common in marmosets and tamarins, a result of fraternal twin or triplet birth patterns in which connected circulatory systems (through which stem...
4.
Krienen F, Levandowski K, Zaniewski H, Del Rosario R, Schroeder M, Goldman M, et al.
Sci Adv
. 2023 Oct;
9(41):eadk3986.
PMID: 37824615
The mammalian brain is composed of many brain structures, each with its own ontogenetic and developmental history. We used single-nucleus RNA sequencing to sample over 2.4 million brain cells across...
5.
Saunders A, Huang K, Vondrak C, Hughes C, Smolyar K, Sen H, et al.
Nat Commun
. 2022 Nov;
13(1):6993.
PMID: 36384944
Brain function depends on synaptic connections between specific neuron types, yet systematic descriptions of synaptic networks and their molecular properties are not readily available. Here, we introduce SBARRO (Synaptic Barcode...
6.
Krienen F, Goldman M, Zhang Q, Del Rosario R, Florio M, Machold R, et al.
Nature
. 2020 Nov;
588(7837):E17.
PMID: 33230336
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
7.
Krienen F, Goldman M, Zhang Q, Del Rosario R, Florio M, Machold R, et al.
Nature
. 2020 Oct;
586(7828):262-269.
PMID: 32999462
Primates and rodents, which descended from a common ancestor around 90 million years ago, exhibit profound differences in behaviour and cognitive capacity; the cellular basis for these differences is unknown....
8.
Bell A, Mello C, Nemesh J, Brumbaugh S, Wysoker A, McCarroll S
Nature
. 2020 Jun;
583(7815):259-264.
PMID: 32494014
Meiosis, although essential for reproduction, is also variable and error-prone: rates of chromosome crossover vary among gametes, between the sexes, and among humans of the same sex, and chromosome missegregation...
9.
Hammond T, Dufort C, Dissing-Olesen L, Giera S, Young A, Wysoker A, et al.
Immunity
. 2018 Nov;
50(1):253-271.e6.
PMID: 30471926
Microglia, the resident immune cells of the brain, rapidly change states in response to their environment, but we lack molecular and functional signatures of different microglial populations. Here, we analyzed...
10.
Saunders A, Macosko E, Wysoker A, Goldman M, Krienen F, de Rivera H, et al.
Cell
. 2018 Aug;
174(4):1015-1030.e16.
PMID: 30096299
The mammalian brain is composed of diverse, specialized cell populations. To systematically ascertain and learn from these cellular specializations, we used Drop-seq to profile RNA expression in 690,000 individual cells...