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Aldi Kraja

Explore the profile of Aldi Kraja including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 3351
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Recent Articles
1.
Wang H, Nagarajan P, Winkler T, Bentley A, Miller C, Kraja A, et al.
Res Sq . 2024 Jul; PMID: 39070651
Although both short and long sleep duration are associated with elevated hypertension risk, our understanding of their interplay with biological pathways governing blood pressure remains limited. To address this, we...
2.
Noordam R, Bos M, Wang H, Winkler T, Bentley A, Kilpelainen T, et al.
Nat Commun . 2019 Nov; 10(1):5121. PMID: 31719535
Both short and long sleep are associated with an adverse lipid profile, likely through different biological pathways. To elucidate the biology of sleep-associated adverse lipid profile, we conduct multi-ancestry genome-wide...
3.
Ma X, Mani K, Liu H, Kovacs A, Murphy J, Foroughi L, et al.
J Am Heart Assoc . 2019 Feb; 8(4):e010866. PMID: 30773991
Background Mutations in αB-crystallin result in proteotoxic cardiomyopathy with desmin mislocalization to protein aggregates. Intermittent fasting ( IF ) is a novel approach to activate transcription factor EB (TFEB), a...
4.
Giri A, Hellwege J, Keaton J, Park J, Qiu C, Warren H, et al.
Nat Genet . 2018 Dec; 51(1):51-62. PMID: 30578418
In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts of blood pressure homeostasis. We discovered 208 novel common...
5.
Jackson V, Latourelle J, Wain L, Smith A, Grove M, Bartz T, et al.
Wellcome Open Res . 2018 Sep; 3:4. PMID: 30175238
Over 90 regions of the genome have been associated with lung function to date, many of which have also been implicated in chronic obstructive pulmonary disease. We carried out meta-analyses...
6.
Singh J, Minster R, Schupf N, Kraja A, Liu Y, Christensen K, et al.
J Gerontol A Biol Sci Med Sci . 2017 Mar; 72(10):1411-1416. PMID: 28329217
Background: Identification of genes or fundamental biological pathways that regulate aging phenotypes and longevity could lead to possible interventions to increase healthy longevity. Methods: Using data from the Long Life...
7.
Koboldt D, Kanchi K, Gui B, Larson D, Fulton R, Isaacs W, et al.
Cancer Epidemiol Biomarkers Prev . 2016 Aug; 25(11):1456-1463. PMID: 27486019
Background: Common variants have been associated with prostate cancer risk. Unfortunately, few are reproducibly linked to aggressive disease, the phenotype of greatest clinical relevance. One possible explanation is that rare...
8.
Musani S, Fox E, Kraja A, Bidulescu A, Lieb W, Lin H, et al.
Circ Cardiovasc Genet . 2015 Jan; 8(1):122-30. PMID: 25561047
Background: Numerous experimental studies suggest that B-type natriuretic peptide (BNP) is cardioprotective; however, in clinical studies, higher plasma BNP concentrations have been associated with incident cardiovascular disease and higher left...
9.
Ng M, Shriner D, Chen B, Li J, Chen W, Guo X, et al.
PLoS Genet . 2014 Aug; 10(8):e1004517. PMID: 25102180
Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more...
10.
Miedema M, Petrone A, Arnett D, Dodson J, Carr J, Pankow J, et al.
Circ Cardiovasc Imaging . 2013 Dec; 7(1):52-7. PMID: 24336983
Background: Adult height has been hypothesized to be inversely associated with coronary heart disease; however, studies have produced conflicting results. We sought to examine the relationship between adult height and...