Alberto J Lopez
Overview
Explore the profile of Alberto J Lopez including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
683
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Recent Articles
21.
Alaghband Y, Kwapis J, Lopez A, White A, Aimiuwu O, Al-Kachak A, et al.
Neurobiol Learn Mem
. 2017 Sep;
145:94-104.
PMID: 28890149
Histone deacetylases (HDACs) are chromatin modifying enzymes that have been implicated as powerful negative regulators of memory processes. HDAC3has been shown to play a pivotal role in long-term memory for...
22.
Kwapis J, Alaghband Y, Lopez A, White A, Campbell R, Dang R, et al.
Neuropsychopharmacology
. 2016 Dec;
42(6):1284-1294.
PMID: 27924874
Histone acetylation is a fundamental epigenetic mechanism that is dynamically regulated during memory formation. Histone acetyltransferases (HATs) and histone deacetylases (HDACs) compete to modulate histone acetylation, allowing for rapid changes...
23.
White A, Kramar E, Lopez A, Kwapis J, Doan J, Saldana D, et al.
Nat Commun
. 2016 May;
7:11725.
PMID: 27226355
Recent evidence implicates epigenetic mechanisms in drug-associated memory processes. However, a possible role for one major epigenetic mechanism, nucleosome remodelling, in drug-associated memories remains largely unexplored. Here we examine mice...
24.
Xu X, Sun Y, Holmes T, Lopez A
J Comp Neurol
. 2016 May;
524(17):3666-3673.
PMID: 27150503
The hippocampal formation is traditionally viewed as having a feedforward, unidirectional circuit organization that promotes propagation of excitatory processes. While the substantial forward projection from hippocampal CA1 to the subiculum...
25.
Lopez A, Kramar E, Matheos D, White A, Kwapis J, Vogel-Ciernia A, et al.
J Neurosci
. 2016 Mar;
36(12):3588-99.
PMID: 27013687
Significance Statement: This study evaluates the efficacy of designer receptors exclusively activated by designer drug (DREADDs) as a means of bidirectionally modulating the hippocampus in not only a hippocampus-dependent task...
26.
Li C, Sugam J, Lowery-Gionta E, McElligott Z, McCall N, Lopez A, et al.
Neuropsychopharmacology
. 2016 Jan;
41(8):2122-32.
PMID: 26792442
The periaqueductal gray (PAG) is a brain region involved in nociception modulation, and an important relay center for the descending nociceptive pathway through the rostral ventral lateral medulla. Given the...
27.
Lopez A, Wood M
Front Behav Neurosci
. 2015 May;
9:100.
PMID: 25954173
It is becoming increasingly important to understand how epigenetic mechanisms control gene expression during neurodevelopment. Two epigenetic mechanisms that have received considerable attention are DNA methylation and histone acetylation. Human...
28.
Marcinkiewcz C, Dorrier C, Lopez A, Kash T
Neuropharmacology
. 2014 Sep;
89:157-67.
PMID: 25229718
One of the hallmarks of alcohol dependence is the presence of a withdrawal syndrome during abstinence, which manifests as physical craving for alcohol accompanied by subjective feelings of anxiety. Using...
29.
Li C, McCall N, Lopez A, Kash T
Alcohol
. 2013 Apr;
47(4):279-87.
PMID: 23597415
The role of dopamine (DA) signaling in regulating the rewarding properties of drugs, including alcohol, has been widely studied. The majority of these studies, however, have focused on the DA...