Alberto J Lopez
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Explore the profile of Alberto J Lopez including associated specialties, affiliations and a list of published articles.
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28
Citations
683
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Recent Articles
1.
Farahbakhsh Z, Holleran K, Sens J, Fordahl S, Mauterer M, Lopez A, et al.
Nat Commun
. 2025 Feb;
16(1):1944.
PMID: 39994195
Alcohol use disorder is marked by disrupted behavioral and emotional states which persist into abstinence. The enduring synaptic alterations that remain despite the absence of alcohol are of interest for...
2.
Thibeault K, Leonard M, Kondev V, Emerson S, Bethi R, Lopez A, et al.
Biol Psychiatry
. 2024 Jun;
97(6):590-601.
PMID: 38901723
Background: Substance use disorder is characterized by long-lasting changes in reward-related brain regions, such as the nucleus accumbens. Previous work has shown that cocaine exposure induces plasticity in broad, genetically...
3.
Farahbakhsh Z, Holleran K, Sens J, Fordahl S, Mauterer M, Lopez A, et al.
bioRxiv
. 2024 Apr;
PMID: 38559169
Alcohol use disorder is marked by disrupted behavioral and emotional states which persist into abstinence. The enduring synaptic alterations that remain despite the absence of alcohol are of interest for...
4.
Serotonin modulates an inhibitory input to the central amygdala from the ventral periaqueductal gray
Hon O, DiBerto J, Mazzone C, Sugam J, Bloodgood D, Hardaway J, et al.
Neuropsychopharmacology
. 2022 Aug;
47(13):2194-2204.
PMID: 35999277
Fear is an adaptive state that drives defensive behavioral responses to specific and imminent threats. The central nucleus of the amygdala (CeA) is a critical site of adaptations that are...
5.
Lopez A, Johnson A, Euston T, Wilson R, Nolan S, Brady L, et al.
Commun Biol
. 2021 Jul;
4(1):883.
PMID: 34272455
Substance use disorder (SUD) is a chronic neuropsychiatric condition characterized by long-lasting alterations in the neural circuitry regulating reward and motivation. Substantial work has focused on characterizing the molecular substrates ...
6.
Campbell R, Chen S, Beardwood J, Lopez A, Pham L, Keiser A, et al.
Neuropsychopharmacology
. 2021 Jun;
46(10):1768-1779.
PMID: 34155331
During the initial stages of drug use, cocaine-induced neuroadaptations within the ventral tegmental area (VTA) are critical for drug-associated cue learning and drug reinforcement processes. These neuroadaptations occur, in part,...
7.
Lopez A, Hecking J, White A
Int J Mol Sci
. 2020 Sep;
21(18).
PMID: 32957495
Long-term memory formation requires coordinated regulation of gene expression and persistent changes in cell function. For decades, research has implicated histone modifications in regulating chromatin compaction necessary for experience-dependent changes...
8.
Lopez A, Johnson A, Kunnath A, Morris A, Zachry J, Thibeault K, et al.
Exp Clin Psychopharmacol
. 2020 Jul;
29(4):319-333.
PMID: 32658535
Substance use disorder (SUD) is a behavioral disorder characterized by volitional drug consumption. Mouse models of SUD allow for the use of molecular, genetic, and circuit-level tools, providing enormous potential...
9.
Kutlu M, Zachry J, Brady L, Melugin P, Kelly S, Sanders C, et al.
Neuropsychopharmacology
. 2020 May;
45(9):1463-1472.
PMID: 32375157
A large body of work has focused on understanding stimulus-driven behavior, sex differences in these processes, and the neural circuits underlying them. Many preclinical mouse models present rewarding or aversive...
10.
Lopez A, Siciliano C, Calipari E
Handb Exp Pharmacol
. 2019 Oct;
258:231-263.
PMID: 31628597
Substance use disorder (SUD) is a behavioral disorder characterized by cycles of abstinence, drug seeking, and relapse. SUD is characterized by aberrant learning processes which develop after repeated exposure to...