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Alberto Galbusera

Explore the profile of Alberto Galbusera including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 923
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Recent Articles
11.
Montani C, Canella C, Schwarz A, Li J, Gilmour G, Galbusera A, et al.
Neuropsychopharmacology . 2020 Dec; 46(6):1194-1206. PMID: 33342996
Cholinergic drugs acting at M1/M4 muscarinic receptors hold promise for the treatment of symptoms associated with brain disorders characterized by cognitive impairment, mood disturbances, or psychosis, such as Alzheimer's disease...
12.
Nuzzo T, Sekine M, Punzo D, Miroballo M, Katane M, Saitoh Y, et al.
Biochim Biophys Acta Proteins Proteom . 2020 Aug; 1868(12):140531. PMID: 32853769
Background: Autism spectrum disorders (ASD) comprise a heterogeneous group of neurodevelopmental conditions characterized by impairment in social interaction, deviance in communication, and repetitive behaviors. Dysfunctional ionotropic NMDA and AMPA receptors,...
13.
Pagani M, de Felice A, Montani C, Galbusera A, Papaleo F, Gozzi A
Neuroscience . 2020 Jan; 445:83-94. PMID: 31917352
Central release of the neuropeptide oxytocin (OXT) modulates neural substrates involved in socio-affective behavior. This property has prompted research into the use of intranasal OXT administration as an adjunctive therapy...
14.
Pagani M, Bertero A, Liska A, Galbusera A, Sabbioni M, Barsotti N, et al.
J Neurosci . 2019 May; 39(27):5299-5310. PMID: 31061091
Mutations in the synaptic scaffolding protein SHANK3 are a major cause of autism and are associated with prominent intellectual and language deficits. However, the neural mechanisms whereby SHANK3 deficiency affects...
15.
Chelini G, Zerbi V, Cimino L, Grigoli A, Markicevic M, Libera F, et al.
J Neurosci . 2018 Dec; 39(8):1525-1538. PMID: 30593497
Overreactivity and defensive behaviors in response to tactile stimuli are common symptoms in autism spectrum disorder (ASD) patients. Similarly, somatosensory hypersensitivity has also been described in mice lacking ASD-associated genes...
16.
Maddaloni G, Migliarini S, Napolitano F, Giorgi A, Nazzi S, Biasci D, et al.
Sci Rep . 2018 Aug; 8(1):11847. PMID: 30087403
Abnormal hippocampal neural plasticity has been implicated in behavioural abnormalities and complex neuropsychiatric conditions, including bipolar disorder (BD). However, the determinants of this neural alteration remain unknown. This work tests...
17.
Bertero A, Liska A, Pagani M, Parolisi R, Esteban Masferrer M, Gritti M, et al.
Brain . 2018 May; 141(7):2055-2065. PMID: 29722793
Human genetic studies are rapidly identifying variants that increase risk for neurodevelopmental disorders. However, it remains unclear how specific mutations impact brain function and contribute to neuropsychiatric risk. Chromosome 16p11.2...
18.
Suetterlin P, Hurley S, Mohan C, Riegman K, Pagani M, Caruso A, et al.
Cereb Cortex . 2018 Apr; 28(6):2192-2206. PMID: 29668850
Truncating CHD8 mutations are amongst the highest confidence risk factors for autism spectrum disorder (ASD) identified to date. Here, we report that Chd8 heterozygous mice display increased brain size, motor...
19.
Giorgi A, Migliarini S, Galbusera A, Maddaloni G, Mereu M, Margiani G, et al.
Cell Rep . 2017 Oct; 21(4):910-918. PMID: 29069598
Serotonin-producing neurons profusely innervate brain regions via long-range projections. However, it remains unclear whether and how endogenous serotonergic transmission specifically influences regional or global functional activity. We combined designed receptors...
20.
Michetti C, Caruso A, Pagani M, Sabbioni M, Medrihan L, David G, et al.
Cereb Cortex . 2017 Sep; 27(10):5014-5023. PMID: 28922833
Autism spectrum disorders (ASD) and epilepsy are neurodevelopmental conditions that appear with high rate of co-occurrence, suggesting the possibility of a common genetic basis. Mutations in Synapsin (SYN) genes, particularly...