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Albert Adell

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Articles 48
Citations 1271
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Recent Articles
1.
Sanchez-Fernandez N, Gomez-Acero L, Castane A, Adell A, Campa L, Bonaventura J, et al.
Neurotherapeutics . 2024 Sep; 21(5):e00439. PMID: 39232876
A combination of Δ-tetrahydrocannabinol (Δ-THC) and cannabidiol (CBD) at non-psychoactive doses was previously demonstrated to reduce cognitive decline in APP/PS1 mice, an animal model of Alzheimer's disease (AD). However, the...
2.
Alfosea-Cuadrado G, Zarzoso-Foj J, Adell A, Valverde-Navarro A, Gonzalez-Soler E, Mangas-Sanjuan V, et al.
Pharmaceutics . 2024 Aug; 16(8). PMID: 39204446
(1) Background: Fibromyalgia syndrome (FMS) is a chronic pain condition with widespread pain and multiple comorbidities, for which conventional therapies offer limited benefits. The reserpine-induced myalgia (RIM) model is an...
3.
Sanchez-Sanchez L, Garcia J, Fernandez R, Noskova E, Egiguren-Ortiz J, Gulak M, et al.
Int J Mol Sci . 2023 Feb; 24(4). PMID: 36835247
Cannabis has been used for decades as a palliative therapy in the treatment of cancer. This is because of its beneficial effects on the pain and nausea that patients can...
4.
Garro-Aguilar Y, Fernandez R, Calero S, Noskova E, Gulak M, de la Fuente M, et al.
Molecules . 2023 Feb; 28(3). PMID: 36770644
Producers of milk and dairy products have been faced with the challenge of responding to European society's demand for guaranteed animal welfare production. In recent years, measures have been taken...
5.
Noskova E, Fernandez R, Garcia J, Ochoa E, Dominguez-Fernandez C, Adell A, et al.
Int J Mol Sci . 2023 Jan; 24(2). PMID: 36674832
The development of strains with high cannabidiol (CBD) and low tetrahydrocannabinol (THC) content is a growing field of research, both for medical and recreational use. However, the mechanisms behind clinical...
6.
Cabanu S, Pilar-Cuellar F, Zubakina P, Florensa-Zanuy E, Senserrich J, Newman-Tancredi A, et al.
Pharmaceuticals (Basel) . 2022 Mar; 15(3). PMID: 35337135
Depression is the most prevalent of the mental illnesses and serotonin (5-hydroxytryptamine, 5-HT) is considered to be the major neurotransmitter involved in its etiology and treatment. In this context, 5-HT...
7.
Merino E, Raya-Salom D, Teruel-Marti V, Adell A, Cervera-Ferri A, Martinez-Ricos J
Neuroscience . 2021 Sep; 476:72-89. PMID: 34543675
Displaying a stress response to threatening stimuli is essential for survival. These reactions must be adjusted to be adaptive. Otherwise, even mental illnesses may develop. Describing the physiological stress response...
8.
Garro-Martinez E, Fullana M, Florensa-Zanuy E, Senserrich J, Paz V, Ruiz-Bronchal E, et al.
Int J Mol Sci . 2021 Aug; 22(16). PMID: 34445375
Fast and sustained antidepressant effects of ketamine identified the mammalian target of rapamycin (mTOR) signaling pathway as the main modulator of its antidepressive effects. Thus, mTOR signaling has become integral...
9.
Pascual-Anton R, Blasco-Serra A, Munoz-Moreno E, Pilar-Cuellar F, Garro-Martinez E, Florensa-Zanuy E, et al.
Brain Struct Funct . 2021 Aug; 226(8):2603-2616. PMID: 34363521
Ketamine has rapid and robust antidepressant effects. However, unwanted psychotomimetic effects limit its widespread use. Hence, several studies examined whether GluN2B-subunit selective NMDA antagonists would exhibit a better therapeutic profile....
10.
Florensa-Zanuy E, Garro-Martinez E, Adell A, Castro E, Diaz A, Pazos A, et al.
Biochem Pharmacol . 2021 Jan; 185:114433. PMID: 33513342
Major Depression is a severe psychiatric condition with a still poorly understood etiology. In the last years, evidence supporting the neuroinflammatory hypothesis of depression has increased. In the current clinical...