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Alastair J Flint

Explore the profile of Alastair J Flint including associated specialties, affiliations and a list of published articles. Areas
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Articles 123
Citations 1073
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Whitmore C, Neil-Sztramko S, Grenier S, Gough A, Goodarzi Z, Weir E, et al.
PLoS One . 2024 Dec; 19(12):e0315185. PMID: 39693333
Background: Anxiety disorders are prevalent amongst older adults and negatively impact their quality-of-life and health. Anxiety disorders often go undetected or are misattributed to age-related changes. The aim of this...
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Rajji T, Bowie C, Herrmann N, Pollock B, Lanctot K, Kumar S, et al.
JAMA Psychiatry . 2024 Oct; 82(1):12-21. PMID: 39476073
Importance: Older adults with major depressive disorder (MDD) or mild cognitive impairment (MCI) are at high risk for cognitive decline. Objective: To assess the efficacy of cognitive remediation (CR) plus...
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Choi J, Beroncal E, Chernega T, Brooks H, Kennedy J, Fisher C, et al.
Transl Psychiatry . 2024 Oct; 14(1):457. PMID: 39468012
Mild cognitive impairment (MCI) is a prodromal stage in aging to possible progression to Alzheimer's disease and related dementia (ADRD), where co-occurrence of major depressive disorder (MDD) accelerates the progression....
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Ihaddadene R, Alexopoulos G, Marino P, Meyers B, Mulsant B, Neufeld N, et al.
Psychiatry Res . 2024 Sep; 342:116192. PMID: 39299145
Little is known about factors that contribute to attrition in clinical trials of the pharmacotherapy of psychotic depression. The purpose of this study was to identify factors associated with attrition...
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Mak M, Gebara M, Lenze E, Blumberger D, Brown P, Cristancho P, et al.
Am J Geriatr Psychiatry . 2024 Aug; 33(1):63-72. PMID: 39209616
Background: Adults with treatment-resistant late-life depression (TRLLD) have high rates of sleep problems; however, little is known about the occurrence and change in sleep during pharmacotherapy of TRLLD. This analysis...
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Kim H, Lenze E, Ainsworth N, Blumberger D, Brown P, Flint A, et al.
J Affect Disord . 2024 Jun; 361:651-658. PMID: 38925306
Background: The Patient Health Questionnaire (PHQ-9) and Montgomery-Asberg Depression Rating Scale (MADRS) are commonly used scales to measure depression severity in older adults. Methods: We utilized data from the Optimizing...
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Patterson R, Brooks H, Mirjalili M, Rashidi-Ranjbar N, Zomorrodi R, Blumberger D, et al.
Cogn Neurodyn . 2024 Jun; 18(3):795-811. PMID: 38826646
Supplementary Information: The online version contains supplementary material available at 10.1007/s11571-023-09938-y.
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Levy A, Grigorovich A, McMurray J, Quirt H, Ranft K, Engell K, et al.
BMC Health Serv Res . 2024 Apr; 24(1):481. PMID: 38637814
Background: Healthcare providers may experience moral distress when they are unable to take the ethically or morally appropriate action due to real or perceived constraints in delivering care, and this...
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Kim H, Voineskos A, Neufeld N, Alexopoulos G, Bingham K, Flint A, et al.
Mol Psychiatry . 2024 Mar; 29(8):2459-2466. PMID: 38503927
Some data suggest that antipsychotics may adversely affect brain structure. We examined the relationship among olanzapine exposure, relapse, and changes in brain structure in patients with major depressive disorder with...