Alan S Beedle
Overview
Explore the profile of Alan S Beedle including associated specialties, affiliations and a list of published articles.
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15
Citations
1062
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Recent Articles
1.
Gluckman P, Low F, Buklijas T, Hanson M, Beedle A
Evol Appl
. 2015 Jan;
4(2):249-63.
PMID: 25567971
An appreciation of the fundamental principles of evolutionary biology provides new insights into major diseases and enables an integrated understanding of human biology and medicine. However, there is a lack...
2.
Gluckman P, Beedle A, Hanson M, Low F
Nestle Nutr Inst Workshop Ser
. 2013 Mar;
71:89-102.
PMID: 23502143
Evolutionary and life history perspectives allow a fuller understanding of both patterns of growth and development and variations in disease risk. Evolutionary processes act to ensure successful reproduction and not...
3.
Forrester T, Badaloo A, Boyne M, Osmond C, Thompson D, Green C, et al.
PLoS One
. 2012 May;
7(4):e35907.
PMID: 22558267
Background: Severe acute malnutrition in childhood manifests as oedematous (kwashiorkor, marasmic kwashiorkor) and non-oedematous (marasmus) syndromes with very different prognoses. Kwashiorkor differs from marasmus in the patterns of protein, amino...
4.
Gluckman P, Beedle A
Dev Psychol
. 2012 May;
48(3):643-6.
PMID: 22545849
The application of evolutionary thinking to human physical and psychological medicine suggests several pathways through which evolutionary processes affect risk of disease. Among these is the concept of mismatch between...
5.
Sloboda D, Beedle A, Cupido C, Gluckman P, Vickers M
Curr Gerontol Geriatr Res
. 2009 Sep;
:608740.
PMID: 19746180
Life history theory proposes that early-life cues induce highly integrated responses in traits associated with energy partitioning, maturation, reproduction, and aging such that the individual phenotype is adaptively more appropriate...
6.
Gluckman P, Hanson M, Buklijas T, Low F, Beedle A
Nat Rev Endocrinol
. 2009 Jun;
5(7):401-8.
PMID: 19488075
Cellular commitment to a specific lineage is controlled by differential silencing of genes, which in turn depends on epigenetic processes such as DNA methylation and histone modification. During early embryogenesis,...
7.
Gluckman P, Hanson M, Bateson P, Beedle A, Law C, Bhutta Z, et al.
Lancet
. 2009 May;
373(9675):1654-7.
PMID: 19427960
No abstract available.
8.
Developmental perspectives on individual variation: implications for understanding nutritional needs
Gluckman P, Beedle A, Hanson M, Yap E
Nestle Nutr Workshop Ser Pediatr Program
. 2008 Jul;
62:1-9.
PMID: 18626189
Genetic research has focused on identifying linkages between polymorphisms and phenotypic traits to explain variations in complex biologies. However, the magnitude of these linkages has not been particularly high. Conversely,...
9.
Gluckman P, Hanson M, Beedle A, Spencer H
Trends Endocrinol Metab
. 2008 Mar;
19(4):109-10.
PMID: 18328727
No abstract available.
10.
Gluckman P, Hanson M, Beedle A, Raubenheimer D
Front Horm Res
. 2008 Jan;
36:61-72.
PMID: 18230894
Evolutionary and developmental perspectives add considerably to our understanding of the aetiology of obesity and its related disorders. One pathway to obesity represents the maladaptive consequences of an evolutionarily preserved...