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Alan Leff

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Articles 5
Citations 256
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Recent Articles
1.
Meng F, Mambetsariev I, Tian Y, Beckham Y, Meliton A, Leff A, et al.
Am J Respir Cell Mol Biol . 2014 Jul; 52(2):152-61. PMID: 24992633
Reversible changes in lung microstructure accompany lung inflammation, although alterations in tissue micromechanics and their impact on inflammation remain unknown. This study investigated changes in extracellular matrix (ECM) remodeling and...
2.
Kratzer E, Tian Y, Sarich N, Wu T, Meliton A, Leff A, et al.
Am J Respir Cell Mol Biol . 2012 Jul; 47(5):688-97. PMID: 22842495
Oxidative stress is an important part of host innate immune response to foreign pathogens, such as bacterial LPS, but excessive activation of redox signaling may lead to pathologic endothelial cell...
3.
Birukova A, Wu T, Tian Y, Meliton A, Sarich N, Tian X, et al.
Eur Respir J . 2012 Jul; 41(1):165-76. PMID: 22790920
The protective effects of prostacyclin and its stable analogue iloprost are mediated by elevation of intracellular cyclic AMP (cAMP) leading to enhancement of the peripheral actin cytoskeleton and cell-cell adhesive...
4.
Birukova A, Tian Y, Meliton A, Leff A, Wu T, Birukov K
Am J Physiol Lung Cell Mol Physiol . 2012 Feb; 302(9):L965-75. PMID: 22345573
Most patients with acute lung injury (ALI) and acute respiratory distress syndrome of septic and nonseptic nature require assisted ventilation with positive pressure, which at suboptimal range may further exacerbate...
5.
Bates J, Irvin C, Brusasco V, Drazen J, Fredberg J, Loring S, et al.
Am J Respir Cell Mol Biol . 2004 Aug; 31(3):373-4. PMID: 15317683
No abstract available.