Alan G Ryder
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Explore the profile of Alan G Ryder including associated specialties, affiliations and a list of published articles.
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Articles
54
Citations
233
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Recent Articles
1.
de Castro M, Ryder A
J Colloid Interface Sci
. 2025 Jan;
685:843-853.
PMID: 39864393
Poly-N-isopropylacrylamide (PNIPAm), a thermorresponsive polymer, highly soluble in water below its lower critical solution temperature (LCST), is widely used in biomedical applications like drug delivery. Being able to measure PNIPAm...
2.
Boateng B, Ryder A
J Biotechnol
. 2024 Oct;
395:205-215.
PMID: 39389363
Biopharmaceutical process development often involves the use of small-scale bioreactors (SSBR) for optimizing media formulations and process conditions during scale up to commercial scale production. Two key process parameters (CPP)...
3.
Kyne M, de Faria E Silva A, Vickroy B, Ryder A
J Biotechnol
. 2023 Sep;
376:1-10.
PMID: 37689251
Yeastolate is often used as a media supplement in industrial mammalian cell culture or as a major media component for microbial fermentations. Yeastolate variability can significantly affect process performance, but...
4.
de Faria E Silva A, Ryder A
Biotechnol Bioeng
. 2022 Sep;
119(12):3432-3446.
PMID: 36071600
Antibody-drug conjugates (ADCs) are promising anticancer therapeutics, which offer important advantages compared to more classical therapies. There are a variety of ADC critical quality attributes (CQAs) such as the protein...
5.
Gordon F, Casamayou-Boucau Y, Ryder A
Colloids Surf B Biointerfaces
. 2022 Jan;
211:112310.
PMID: 35007857
Studying the interaction between plasma proteins and liposomes is critical, particularly for their use as drug delivery systems. Here, the efficacy of anisotropy resolved multidimensional emission spectroscopy (ARMES) for investigating...
6.
van Zanten C, Melnikau D, Ryder A
J Fluoresc
. 2021 Mar;
31(3):835-845.
PMID: 33740150
Fluorescence Correlation Spectroscopy (FCS) studies of the interaction of polymers or proteins in solution are strongly affected by the viscosity and refractive index of the medium, and the effects are...
7.
Boateng B, Elcoroaristizabal S, Ryder A
Biotechnol Bioeng
. 2021 Jan;
118(5):1805-1817.
PMID: 33501639
Protein quantification during bioprocess monitoring is essential for biopharmaceutical manufacturing and is complicated by the complex chemical composition of the bioreactor broth. Here we present the early-stage development and optimization...
8.
Gordon F, Elcoroaristizabal S, Ryder A
Biochim Biophys Acta Gen Subj
. 2020 Nov;
1865(2):129770.
PMID: 33214128
Background: Förster Resonance Energy Transfer (FRET) is widely used to study the structure and dynamics of biomolecular systems and also causes the non-linear fluorescence response observed in multi-fluorophore proteins. Accurate...
9.
Casamayou-Boucau Y, Ryder A
Anal Chim Acta
. 2020 Nov;
1138:18-29.
PMID: 33161979
Being able to measure the size and distribution of oligomers in solution is a critical issue in the manufacture and stability of insulin and other protein formulations. Measuring oligomers reliably...
10.
de Faria E Silva A, Elcoroaristizabal S, Ryder A
Anal Chim Acta
. 2020 Feb;
1101:99-110.
PMID: 32029125
Immunoglobulin G (IgG) is often used as a starting material for the production of functionalised antibodies, like Antibody Drug Conjugates (ADCs), PEGlyated-conjugates, or radioimmunoconjugates. The gross structural quality of the...