Alan D Pemberton
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Explore the profile of Alan D Pemberton including associated specialties, affiliations and a list of published articles.
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Citations
562
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Recent Articles
1.
Forman R, deSchoolmeester M, Hurst R, Wright S, Pemberton A, Else K
PLoS One
. 2012 Sep;
7(9):e42248.
PMID: 22970115
Background: Mouse angiogenin 4 (Ang4) has previously been described as a Paneth cell-derived antimicrobial peptide important in epithelial host defence in the small intestine. However, a source for Ang4 in...
2.
Pemberton A, Brown J, Craig N, Pate J, Mclean K, Inglis N, et al.
Parasitology
. 2011 Nov;
139(3):375-85.
PMID: 22075947
Continual low-level exposure of sheep to the helminth Teladorsagia circumcincta elicits a temporary protective immunity, where factors in the immune abomasal mucosa prevent penetration of infective larvae, but which is...
3.
Burggraf M, Nakajima-Adachi H, Hachimura S, Ilchmann A, Pemberton A, Kiyono H, et al.
Mol Nutr Food Res
. 2011 Jun;
55(10):1475-83.
PMID: 21714123
Scope: Oral immunotherapy (OIT) involving continuous oral administration of allergenic foods has gained attention as a therapy for food allergies. To study the influence of oral administration of allergenic foods...
4.
Athanasiadou S, Jones L, Burgess S, Kyriazakis I, Pemberton A, Houdijk J, et al.
PLoS One
. 2011 Jun;
6(6):e20771.
PMID: 21698235
Background: Gastrointestinal nematode infection is a major challenge to the health and welfare of mammals. Although mammals eventually acquire immunity to nematodes, this breaks down around parturition, which renders periparturient...
5.
Knight P, Griffith S, Pemberton A, Pate J, Guarneri L, Anderson K, et al.
Vet Res
. 2011 Jun;
42:78.
PMID: 21682880
Infection of sheep with the gastric nematode Teladorsagia circumcincta results in distinct Th2-type changes in the mucosa, including mucous neck cell and mast cell hyperplasia, eosinophilia, recruitment of IgA/IgE producing...
6.
Pemberton A, Verdon B, Inglis N, Pearson J
Res Vet Sci
. 2011 Apr;
91(3):e53-7.
PMID: 21453947
Secretion of gastric mucins plays an essential role in host protection, and modifications in mucus properties are characteristic of the protective immune responses to pathogens. This study describes the purification...
7.
Dold C, Pemberton A, Stafford P, Holland C, Behnke J
Parasitology
. 2011 Feb;
138(5):660-9.
PMID: 21349217
The underlying mechanism of predisposition to Ascaris infection is not yet understood but host genetics are thought to play a fundamental role. We investigated the association between the Intelectin-2 gene...
8.
Lu Z, di Domenico A, Wright S, Knight P, Whitelaw C, Pemberton A
BMC Genomics
. 2011 Feb;
12:110.
PMID: 21324158
Background: C57BL/6J mice possess a single intelectin (Itln) gene on chromosome 1. The function of intelectins is not well understood, but roles have been postulated in insulin sensitivity, bacterial recognition,...
9.
Pae S, Cho J, Dayan S, Miller M, Pemberton A, Broide D
Immunogenetics
. 2010 May;
62(8):499-506.
PMID: 20480160
As genetically engineered mutant mice deficient in single genes are usually generated on a C57BL/6 background, to study mast cell trafficking in mutant mice, we initially investigated whether mast cells...
10.
Pemberton A, Brown J
PLoS One
. 2010 Apr;
5(3):e9884.
PMID: 20360839
Background: Nuclear histones have previously been shown to aggregate LDL in vitro, suggestive of a possible pro-atherogenic role. Recent studies indicate that histones are released during acute inflammation, and therefore...