Alpha 2.0
Login Register
» Authors » Alan D Curtis 2nd

Alan D Curtis 2nd

Explore the profile of Alan D Curtis 2nd including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 16
Citations 198
Followers 0
Related Specialties
Allergy & Immunology
Microbiology
Science
Top 10 Co-Authors
Kristina De Paris
Koen K A Van Rompay
Mark D Mannie
Justin Pollara
Pamela A Kozlowski
Sallie R Permar
Maria Dennis
Guido Ferrari
S Munir Alam
Genevieve G Fouda
Published In
PLoS One
Front Immunol
mSphere
Hum Vaccin Immunother
Proc Natl Acad Sci U S A
Affiliations
Soon will be listed here.
Recent Articles
1.
Early Post-Vaccination Gene Signatures Correlate With the Magnitude and Function of Vaccine-Induced HIV Envelope-Specific Plasma Antibodies in Infant Rhesus Macaques
Vijayan K, Cross K, Curtis 2nd A, Van Rompay K, Pollara J, Fox C, et al.
Front Immunol . 2022 May; 13:840976. PMID: 35572573
A better understanding of the impact of early innate immune responses after vaccine priming on vaccine-elicited adaptive immune responses could inform rational design for effective HIV vaccines. The current study...
2.
Vaccine-Induced, High-Magnitude HIV Env-Specific Antibodies with Fc-Mediated Effector Functions Are Insufficient to Protect Infant Rhesus Macaques against Oral SHIV Infection
Curtis 2nd A, Saha P, Dennis M, Berendam S, Ramasubramanian P, Cross K, et al.
mSphere . 2022 Feb; 7(1):e0083921. PMID: 35196125
Improved access to antiretroviral therapy (ART) and antenatal care has significantly reduced and peripartum mother-to-child human immunodeficiency virus (HIV) transmission. However, as breast milk transmission of HIV still occurs at...
3.
Different adjuvanted pediatric HIV envelope vaccines induced distinct plasma antibody responses despite similar B cell receptor repertoires in infant rhesus macaques
Berendam S, Morgan-Asiedu P, Mangan R, Li S, Heimsath H, Luo K, et al.
PLoS One . 2021 Dec; 16(12):e0256885. PMID: 34972105
Different HIV vaccine regimens elicit distinct plasma antibody responses in both human and nonhuman primate models. Previous studies in human and non-human primate infants showed that adjuvants influenced the quality...
4.
SARS-CoV-2 vaccines elicit durable immune responses in infant rhesus macaques
Garrido C, Curtis 2nd A, Dennis M, Pathak S, Gao H, Montefiori D, et al.
Sci Immunol . 2021 Jun; 6(60). PMID: 34131024
The inclusion of infants in the SARS-CoV-2 vaccine roll-out is important to prevent severe complications of pediatric SARS-CoV-2 infections and to limit transmission and could possibly be implemented via the...
5.
HIV Env-Specific IgG Antibodies Induced by Vaccination of Neonatal Rhesus Macaques Persist and Can Be Augmented by a Late Booster Immunization in Infancy
Curtis 2nd A, Dennis M, Eudailey J, Walter K, Cronin K, Alam S, et al.
mSphere . 2020 Mar; 5(2). PMID: 32213623
The HIV epidemics in infants and adolescent women are linked. Young women of childbearing age are at high risk for HIV infection and, due to poor HIV testing rates and...
6.
Functional Perturbation of Mucosal Group 3 Innate Lymphoid and Natural Killer Cells in Simian-Human Immunodeficiency Virus/Simian Immunodeficiency Virus-Infected Infant Rhesus Macaques
Hueber B, Curtis 2nd A, Kroll K, Varner V, Jones R, Pathak S, et al.
J Virol . 2019 Dec; 94(5). PMID: 31801861
Mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) via breastfeeding is responsible for nearly half of new infections of children with HIV. Although innate lymphoid cells (ILC) and natural...
7.
Analytical Treatment Interruption after Short-Term Antiretroviral Therapy in a Postnatally Simian-Human Immunodeficiency Virus-Infected Infant Rhesus Macaque Model
Goswami R, Nelson A, Tu J, Dennis M, Feng L, Kumar A, et al.
mBio . 2019 Sep; 10(5). PMID: 31488511
To achieve long-term viral remission in human immunodeficiency virus (HIV)-infected children, novel strategies beyond early antiretroviral therapy (ART) will be necessary. Identifying clinical predictors of the time to viral rebound...
8.
A GMCSF-Neuroantigen Tolerogenic Vaccine Elicits Systemic Lymphocytosis of CD4 CD25 FOXP3 Regulatory T Cells in Myelin-Specific TCR Transgenic Mice Contingent Upon Low-Efficiency T Cell Antigen Receptor Recognition
Moorman C, Curtis 2nd A, Bastian A, Elliott S, Mannie M
Front Immunol . 2019 Jan; 9:3119. PMID: 30687323
Previous studies showed that single-chain fusion proteins comprised of GM-CSF and major encephalitogenic peptides of myelin, when injected subcutaneously in saline, were potent tolerogenic vaccines that suppressed experimental autoimmune encephalomyelitis...
9.
Oral Coadministration of an Intramuscular DNA/Modified Vaccinia Ankara Vaccine for Simian Immunodeficiency Virus Is Associated with Better Control of Infection in Orally Exposed Infant Macaques
Curtis 2nd A, Walter K, Nabi R, Jensen K, Dwivedi A, Pollara J, et al.
AIDS Res Hum Retroviruses . 2018 Oct; 35(3):310-325. PMID: 30303405
The majority of human immunodeficiency virus (HIV) type 1 infections in infants are acquired orally through breastfeeding. Toward development of a pediatric HIV vaccine to prevent breastmilk transmission, we tested...
10.
A simultaneous oral and intramuscular prime/sublingual boost with a DNA/Modified Vaccinia Ankara viral vector-based vaccine induces simian immunodeficiency virus-specific systemic and mucosal immune responses in juvenile rhesus macaques
Curtis 2nd A, Jensen K, Van Rompay K, Amara R, Kozlowski P, De Paris K
J Med Primatol . 2018 Sep; 47(5):288-297. PMID: 30204253
Background: A pediatric vaccine to prevent breast milk transmission of human immunodeficiency virus (HIV) may generate greater immune responses at viral entry sites if given by an oral route. Methods:...