Alan Altraja
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Explore the profile of Alan Altraja including associated specialties, affiliations and a list of published articles.
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54
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502
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Recent Articles
1.
Laanesoo A, Mae M, Remm A, Johnston S, Altraja A, Bochenek G, et al.
Clin Exp Allergy
. 2025 Feb;
55(3):239-246.
PMID: 39934921
Background: Asthma exacerbations are frequently triggered by human rhinoviruses (RVs). Among other pro-inflammatory responses, RV infection of airway epithelium promotes the activation of the inflammasome pathway, the role of which...
2.
Larenas-Linnemann D, Rhee C, Altraja A, Busby J, Tran T, Wang E, et al.
Tuberc Respir Dis (Seoul)
. 2025 Feb;
PMID: 39915034
The International Severe Asthma Registry (ISAR) was established in 2017 to advance the understanding of severe asthma and its management, thereby improving patient care worldwide. As the first global registry...
3.
von Bulow A, Hansen S, Sandin P, Cooper A, Ernstsson O, Geale K, et al.
J Allergy Clin Immunol Pract
. 2025 Feb;
PMID: 39900241
Background: The link between the use of oral corticosteroids (OCS) and adverse events (AEs) in asthma is well described. In contrast, whether the use of high-dose inhaled corticosteroids (ICS) poses...
4.
Khaleva E, Brightling C, Eiwegger T, Altraja A, Begin P, Blumchen K, et al.
Eur Respir J
. 2024 Nov;
PMID: 39510551
Background: We have previously developed Core Outcome Measures sets for Severe Asthma (COMSA) by multi-stakeholder consensus. There are no patient-centred tools to quantify response to biologics for severe asthma. We...
5.
Le T, Price D, Erhard C, Cook B, Quinton A, Katial R, et al.
J Asthma Allergy
. 2024 Oct;
17:1055-1069.
PMID: 39479509
Introduction: Patients with severe asthma may be prescribed biologic therapies to improve disease control. The EVEREST study aimed to characterize the global disease burden of patients with severe asthma without...
6.
Oit-Wiscombe I, Virag L, Kilk K, Soomets U, Altraja A
Antioxidants (Basel)
. 2024 Aug;
13(8).
PMID: 39199199
To test the hypothesis that they serve as systemic biomarkers of chronic obstructive pulmonary disease (COPD), we profiled the mRNA expression of enzymes connected to systemic inflammation and GSH metabolism...
7.
Denton E, Hew M, Peters M, Upham J, Bulathsinhala L, Tran T, et al.
Allergy
. 2024 Jun;
79(10):2700-2716.
PMID: 38923444
Background: Biologic asthma therapies reduce exacerbations and long-term oral corticosteroids (LTOCS) use in randomized controlled trials (RCTs); however, there are limited data on outcomes among patients ineligible for RCTs. Hence,...
8.
Scelo G, Tran T, Le T, Fageras M, Dorscheid D, Busby J, et al.
J Allergy Clin Immunol Pract
. 2024 May;
12(9):2347-2361.
PMID: 38768896
Background: Biologic effectiveness is often assessed as response, a term that eludes consistent definition. Identifying those most likely to respond in real-life has proven challenging. Objective: To explore definitions of...
9.
Porsbjerg C, Townend J, Bergeron C, Christoff G, Katsoulotos G, Larenas-Linnemann D, et al.
Front Immunol
. 2024 May;
15:1361891.
PMID: 38711495
Background: To date, studies investigating the association between pre-biologic biomarker levels and post-biologic outcomes have been limited to single biomarkers and assessment of biologic efficacy from structured clinical trials. Aim:...
10.
Perez-de-Llano L, Scelo G, Tran T, Le T, Fageras M, Cosio B, et al.
Am J Respir Crit Care Med
. 2024 May;
210(7):869-880.
PMID: 38701495
There is no consensus on criteria to include in an asthma remission definition in real life. Factors associated with achieving remission after biologic initiation remain poorly understood. To quantify the...